Detailed information NTG0190702

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: A6L46_RS08060
• Genome accession: NZ_CP016660
• Coordinates: 1554587..1555036 (-)
• Length: 149 a.a.
• NCBI ID: WP_002214937.1
• Uniprot ID: A0AA44U8B7
• Organism: Neisseria meningitidis strain M22804
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1552388..1553601	1554587..1555036	flank	986

Gene organization within MGE regions

Location: 1552388..1555036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L46_RS08045 (A6L46_08045)	-	1553128..1553601 (-)	474	Protein_1487	transposase	-
A6L46_RS08050 (A6L46_08050)	-	1553833..1554045 (+)	213	WP_002224145.1	SWIM zinc finger family protein	-
A6L46_RS14895 (A6L46_08055)	-	1554229..1554497 (+)	269	Protein_1489	5'-nucleotidase	-
A6L46_RS08060 (A6L46_08060)	comP	1554587..1555036 (-)	450	WP_002214937.1	type IV pilin protein	Machinery gene

Sequence

Protein

• Length: 149 a.a.
• Molecular weight: 16834.81 Da
• Isoelectric Point: 9.7951

>NTDB_id=190702 A6L46_RS08060 WP_002214937.1 1554587..1555036(-) (comP) [Neisseria meningitidis strain M22804]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide

• Length: 450 bp

>NTDB_id=190702 A6L46_RS08060 WP_002214937.1 1554587..1555036(-) (comP) [Neisseria meningitidis strain M22804]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (28-107)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-27)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria gonorrhoeae MS11	100	100	1
comP	Neisseria meningitidis 8013	99.329	100	0.993
comP	Neisseria subflava NJ9703	49.66	98.658	0.49