Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6L25_RS11010 Genome accession   NZ_CP016652
Coordinates   2131263..2131727 (+) Length   154 a.a.
NCBI ID   WP_025463168.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M08001     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2121212..2134327 2131263..2131727 within 0
IS/Tn 2132603..2133256 2131263..2131727 flank 876


Gene organization within MGE regions


Location: 2121212..2134327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L25_RS10960 (A6L25_10960) - 2121212..2121871 (+) 660 WP_002218694.1 NYN domain-containing protein -
  A6L25_RS10965 (A6L25_10965) dsbA2 2122042..2122737 (+) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6L25_RS10970 (A6L25_10970) ffh 2123068..2124438 (-) 1371 WP_002221448.1 signal recognition particle protein -
  A6L25_RS10975 (A6L25_10975) - 2124658..2125464 (+) 807 WP_002221447.1 cytochrome C assembly family protein -
  A6L25_RS11010 (A6L25_11010) comE 2131263..2131727 (+) 465 WP_025463168.1 ComEA family DNA-binding protein Machinery gene
  A6L25_RS11015 (A6L25_11015) - 2131839..2132045 (+) 207 WP_025461473.1 hypothetical protein -
  A6L25_RS11025 (A6L25_11025) - 2132603..2133256 (+) 654 WP_002241060.1 IS1595 family transposase -
  A6L25_RS11030 (A6L25_11030) - 2133421..2133630 (+) 210 Protein_2055 transposase -
  A6L25_RS11035 (A6L25_11035) - 2133612..2133869 (-) 258 WP_002241061.1 membrane protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16561.83 Da        Isoelectric Point: 10.9695

>NTDB_id=190337 A6L25_RS11010 WP_025463168.1 2131263..2131727(+) (comE) [Neisseria meningitidis strain M08001]
MLYPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPVLPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=190337 A6L25_RS11010 WP_025463168.1 2131263..2131727(+) (comE) [Neisseria meningitidis strain M08001]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGCGCGCCCGCACCAAAAGCCCCAGCCAAACCGGTGCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment