Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA2   Type   Machinery gene
Locus tag   A6L25_RS10965 Genome accession   NZ_CP016652
Coordinates   2122042..2122737 (+) Length   231 a.a.
NCBI ID   WP_002215704.1    Uniprot ID   Q7DDR6
Organism   Neisseria meningitidis strain M08001     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2121212..2134327 2122042..2122737 within 0


Gene organization within MGE regions


Location: 2121212..2134327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L25_RS10960 (A6L25_10960) - 2121212..2121871 (+) 660 WP_002218694.1 NYN domain-containing protein -
  A6L25_RS10965 (A6L25_10965) dsbA2 2122042..2122737 (+) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6L25_RS10970 (A6L25_10970) ffh 2123068..2124438 (-) 1371 WP_002221448.1 signal recognition particle protein -
  A6L25_RS10975 (A6L25_10975) - 2124658..2125464 (+) 807 WP_002221447.1 cytochrome C assembly family protein -
  A6L25_RS11010 (A6L25_11010) comE 2131263..2131727 (+) 465 WP_025463168.1 ComEA family DNA-binding protein Machinery gene
  A6L25_RS11015 (A6L25_11015) - 2131839..2132045 (+) 207 WP_025461473.1 hypothetical protein -
  A6L25_RS11025 (A6L25_11025) - 2132603..2133256 (+) 654 WP_002241060.1 IS1595 family transposase -
  A6L25_RS11030 (A6L25_11030) - 2133421..2133630 (+) 210 Protein_2055 transposase -
  A6L25_RS11035 (A6L25_11035) - 2133612..2133869 (-) 258 WP_002241061.1 membrane protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 25419.90 Da        Isoelectric Point: 5.1502

>NTDB_id=190336 A6L25_RS10965 WP_002215704.1 2122042..2122737(+) (dsbA2) [Neisseria meningitidis strain M08001]
MKLKTLALTSLTLLALAACSKQAETSVPADSAQSSSSAPAAPAELNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide


Download         Length: 696 bp        

>NTDB_id=190336 A6L25_RS10965 WP_002215704.1 2122042..2122737(+) (dsbA2) [Neisseria meningitidis strain M08001]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGTGT
TCCGGCAGACAGCGCCCAAAGCAGCTCATCTGCTCCGGCAGCCCCTGCTGAGTTGAACGAAGGTGTGAACTACACTGTAT
TGTCTACGCCTATTCCGCAACAGCAGGCCGGTAAAATCGAAGTATTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTCCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATTGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCTGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(65-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7DDR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA2 Neisseria meningitidis MC58

100

100

1
  dsbA1 Neisseria meningitidis MC58

71.245

100

0.719

Multiple sequence alignment