Detailed information NTG0190101

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: A6L47_RS14370
• Genome accession: NZ_CP016647
• Coordinates: 1436078..1436542 (-)
• Length: 154 a.a.
• NCBI ID: WP_164993478.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M22809
• Function: DNA binding (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1428087..1446585	1436078..1436542	within	0
IS/Tn	1434735..1435388	1436078..1436542	flank	690

Gene organization within MGE regions

Location: 1428087..1446585

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L47_RS07500 (A6L47_07500)	-	1428087..1428575 (-)	489	WP_002258458.1	hypothetical protein	-
A6L47_RS07505 (A6L47_07505)	-	1430221..1430466 (-)	246	WP_002212272.1	hypothetical protein	-
A6L47_RS07515 (A6L47_07515)	-	1430578..1431006 (+)	429	WP_002212270.1	CopD family protein	-
A6L47_RS07520 (A6L47_07520)	-	1431018..1431494 (+)	477	WP_002231682.1	CYTH domain-containing protein	-
A6L47_RS07525 (A6L47_07525)	-	1431844..1432332 (-)	489	WP_002218701.1	dihydrofolate reductase	-
A6L47_RS07530 (A6L47_07530)	aroG	1432400..1433455 (-)	1056	WP_002212267.1	3-deoxy-7-phosphoheptulonate synthase AroG	-
A6L47_RS13970	-	1433617..1433844 (-)	228	WP_153310284.1	hypothetical protein	-
A6L47_RS07540 (A6L47_07540)	-	1434122..1434379 (+)	258	WP_002231679.1	membrane protein	-
A6L47_RS07545 (A6L47_07545)	-	1434361..1434570 (-)	210	Protein_1399	transposase	-
A6L47_RS07550 (A6L47_07550)	-	1434735..1435388 (-)	654	WP_019742811.1	IS1595 family transposase	-
A6L47_RS14600	-	1435508..1435966 (-)	459	WP_002234522.1	hypothetical protein	-
A6L47_RS14370 (A6L47_07560)	comE	1436078..1436542 (-)	465	WP_164993478.1	ComEA family DNA-binding protein	Machinery gene
A6L47_RS07595 (A6L47_07595)	-	1442333..1443139 (-)	807	WP_002221447.1	cytochrome C assembly family protein	-
A6L47_RS07600 (A6L47_07600)	ffh	1443359..1444729 (+)	1371	WP_002258651.1	signal recognition particle protein	-
A6L47_RS07605 (A6L47_07605)	dsbA2	1445060..1445755 (-)	696	WP_002234519.1	thiol:disulfide interchange protein DsbA/DsbL	Machinery gene
A6L47_RS07610 (A6L47_07610)	-	1445926..1446585 (-)	660	WP_002218694.1	NYN domain-containing protein	-

Sequence

Protein

• Length: 154 a.a.
• Molecular weight: 16486.82 Da
• Isoelectric Point: 10.9585

>NTDB_id=190101 A6L47_RS14370 WP_164993478.1 1436078..1436542(-) (comE) [Neisseria meningitidis strain M22809]
MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPALPAAKK

Nucleotide

• Length: 465 bp

>NTDB_id=190101 A6L47_RS14370 WP_164993478.1 1436078..1436542(-) (comE) [Neisseria meningitidis strain M22809]
TTGCTTTGCCCGGAAAAAATGTCGGTGATGGCGGGACGGCATCCGTACGGTGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCAGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCGGCTCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (75-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734