Detailed information NTG0190051

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: A6L49_RS14090
• Genome accession: NZ_CP016646
• Coordinates: 277465..277929 (-)
• Length: 154 a.a.
• NCBI ID: WP_164967094.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M22819
• Function: DNA binding (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	269470..287970	277465..277929	within	0
IS/Tn	276122..276775	277465..277929	flank	690

Gene organization within MGE regions

Location: 269470..287970

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L49_RS14650 (A6L49_01375)	-	269470..269958 (-)	489	WP_002258458.1	hypothetical protein	-
A6L49_RS01380 (A6L49_01380)	-	271608..271853 (-)	246	WP_002212272.1	hypothetical protein	-
A6L49_RS01390 (A6L49_01390)	-	271965..272393 (+)	429	WP_002212270.1	CopD family protein	-
A6L49_RS01395 (A6L49_01395)	-	272405..272881 (+)	477	WP_002231682.1	CYTH domain-containing protein	-
A6L49_RS01400 (A6L49_01400)	-	273231..273719 (-)	489	WP_002218701.1	dihydrofolate reductase	-
A6L49_RS01405 (A6L49_01405)	aroG	273787..274842 (-)	1056	WP_002212267.1	3-deoxy-7-phosphoheptulonate synthase AroG	-
A6L49_RS13365	-	275004..275231 (-)	228	WP_153310284.1	hypothetical protein	-
A6L49_RS01415 (A6L49_01415)	-	275509..275766 (+)	258	WP_002231679.1	membrane protein	-
A6L49_RS01420 (A6L49_01420)	-	275748..275957 (-)	210	Protein_261	transposase	-
A6L49_RS01425 (A6L49_01425)	-	276122..276775 (-)	654	WP_019742811.1	IS1595 family transposase	-
A6L49_RS14340	-	276895..277353 (-)	459	WP_002234522.1	hypothetical protein	-
A6L49_RS14090 (A6L49_01435)	comE	277465..277929 (-)	465	WP_164967094.1	helix-hairpin-helix domain-containing protein	Machinery gene
A6L49_RS01470 (A6L49_01470)	-	283718..284524 (-)	807	WP_002221447.1	cytochrome C assembly family protein	-
A6L49_RS01475 (A6L49_01475)	ffh	284744..286114 (+)	1371	WP_002258651.1	signal recognition particle protein	-
A6L49_RS01480 (A6L49_01480)	dsbA2	286445..287140 (-)	696	WP_002234519.1	thiol:disulfide interchange protein DsbA/DsbL	Machinery gene
A6L49_RS01485 (A6L49_01485)	-	287311..287970 (-)	660	WP_002218694.1	NYN domain-containing protein	-

Sequence

Protein

• Length: 154 a.a.
• Molecular weight: 16442.72 Da
• Isoelectric Point: 10.7894

>NTDB_id=190051 A6L49_RS14090 WP_164967094.1 277465..277929(-) (comE) [Neisseria meningitidis strain M22819]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPALPAAKK

Nucleotide

• Length: 465 bp

>NTDB_id=190051 A6L49_RS14090 WP_164967094.1 277465..277929(-) (comE) [Neisseria meningitidis strain M22819]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCGGCTCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (75-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734