Detailed information NTG0190015

Bioinformatically predicted

Overview

• Name: dsbA2
• Type: Machinery gene
• Locus tag: A6L49_RS01480
• Genome accession: NZ_CP016646
• Coordinates: 286445..287140 (-)
• Length: 231 a.a.
• NCBI ID: WP_002234519.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M22819
• Function: DNA binding and uptake; interact with PilQ (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	269470..287970	286445..287140	within	0

Gene organization within MGE regions

Location: 269470..287970

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L49_RS14650 (A6L49_01375)	-	269470..269958 (-)	489	WP_002258458.1	hypothetical protein	-
A6L49_RS01380 (A6L49_01380)	-	271608..271853 (-)	246	WP_002212272.1	hypothetical protein	-
A6L49_RS01390 (A6L49_01390)	-	271965..272393 (+)	429	WP_002212270.1	CopD family protein	-
A6L49_RS01395 (A6L49_01395)	-	272405..272881 (+)	477	WP_002231682.1	CYTH domain-containing protein	-
A6L49_RS01400 (A6L49_01400)	-	273231..273719 (-)	489	WP_002218701.1	dihydrofolate reductase	-
A6L49_RS01405 (A6L49_01405)	aroG	273787..274842 (-)	1056	WP_002212267.1	3-deoxy-7-phosphoheptulonate synthase AroG	-
A6L49_RS13365	-	275004..275231 (-)	228	WP_153310284.1	hypothetical protein	-
A6L49_RS01415 (A6L49_01415)	-	275509..275766 (+)	258	WP_002231679.1	membrane protein	-
A6L49_RS01420 (A6L49_01420)	-	275748..275957 (-)	210	Protein_261	transposase	-
A6L49_RS01425 (A6L49_01425)	-	276122..276775 (-)	654	WP_019742811.1	IS1595 family transposase	-
A6L49_RS14340	-	276895..277353 (-)	459	WP_002234522.1	hypothetical protein	-
A6L49_RS14090 (A6L49_01435)	comE	277465..277929 (-)	465	WP_164967094.1	helix-hairpin-helix domain-containing protein	Machinery gene
A6L49_RS01470 (A6L49_01470)	-	283718..284524 (-)	807	WP_002221447.1	cytochrome C assembly family protein	-
A6L49_RS01475 (A6L49_01475)	ffh	284744..286114 (+)	1371	WP_002258651.1	signal recognition particle protein	-
A6L49_RS01480 (A6L49_01480)	dsbA2	286445..287140 (-)	696	WP_002234519.1	thiol:disulfide interchange protein DsbA/DsbL	Machinery gene
A6L49_RS01485 (A6L49_01485)	-	287311..287970 (-)	660	WP_002218694.1	NYN domain-containing protein	-

Sequence

Protein

• Length: 231 a.a.
• Molecular weight: 25447.95 Da
• Isoelectric Point: 5.1502

>NTDB_id=190015 A6L49_RS01480 WP_002234519.1 286445..287140(-) (dsbA2) [Neisseria meningitidis strain M22819]
MKLKTLALTSLTLLALAACSKQAETSVPADSVQSSSSAPAAPAELNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide

• Length: 696 bp

>NTDB_id=190015 A6L49_RS01480 WP_002234519.1 286445..287140(-) (dsbA2) [Neisseria meningitidis strain M22819]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGCGT
TCCGGCAGACAGCGTCCAAAGCAGCTCATCTGCTCCGGCAGCCCCTGCTGAGTTGAACGAAGGTGTGAACTACACTGTAT
TGTCTACGCCTATTCCGCAACAGCAGGCCGGTAAAATCGAAGTATTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTCCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATTGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCCGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

• Thioredoxin (Thioredoxin_4) (65-212)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dsbA2	Neisseria meningitidis MC58	99.567	100	0.996
dsbA1	Neisseria meningitidis MC58	70.815	100	0.714