Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   A6L49_RS03885 Genome accession   NZ_CP016646
Coordinates   726119..726568 (+) Length   149 a.a.
NCBI ID   WP_065826098.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22819     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 727554..728767 726119..726568 flank 986


Gene organization within MGE regions


Location: 726119..728767
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L49_RS03885 (A6L49_03885) comP 726119..726568 (+) 450 WP_065826098.1 type IV pilin protein Machinery gene
  A6L49_RS14675 (A6L49_03890) - 726658..726998 (-) 341 Protein_713 5'-nucleotidase -
  A6L49_RS03895 (A6L49_03895) - 727110..727322 (-) 213 WP_002224145.1 SWIM zinc finger family protein -
  A6L49_RS03900 (A6L49_03900) - 727554..728027 (+) 474 Protein_715 transposase -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16892.84 Da        Isoelectric Point: 9.6170

>NTDB_id=190023 A6L49_RS03885 WP_065826098.1 726119..726568(+) (comP) [Neisseria meningitidis strain M22819]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKEVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=190023 A6L49_RS03885 WP_065826098.1 726119..726568(+) (comP) [Neisseria meningitidis strain M22819]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGAGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-100)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

99.329

100

0.993
  comP Neisseria meningitidis 8013

98.658

100

0.987
  comP Neisseria subflava NJ9703

48.98

98.658

0.483

Multiple sequence alignment