Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   A6L21_RS10105 Genome accession   NZ_CP016644
Coordinates   1949901..1950350 (-) Length   149 a.a.
NCBI ID   WP_002221685.1    Uniprot ID   A1KW94
Organism   Neisseria meningitidis strain M07162     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1947863..1949204 1949901..1950350 flank 697


Gene organization within MGE regions


Location: 1947863..1950350
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L21_RS10090 (A6L21_10090) - 1947863..1948828 (+) 966 Protein_1890 IS30-like element IS1655 family transposase -
  A6L21_RS10095 (A6L21_10095) - 1948854..1949204 (-) 351 Protein_1891 IS5/IS1182 family transposase -
  A6L21_RS14955 (A6L21_10100) - 1949543..1949811 (+) 269 Protein_1892 5'-nucleotidase -
  A6L21_RS10105 (A6L21_10105) comP 1949901..1950350 (-) 450 WP_002221685.1 type IV pilin protein Machinery gene

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16848.83 Da        Isoelectric Point: 9.7951

>NTDB_id=189953 A6L21_RS10105 WP_002221685.1 1949901..1950350(-) (comP) [Neisseria meningitidis strain M07162]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYIEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=189953 A6L21_RS10105 WP_002221685.1 1949901..1950350(-) (comP) [Neisseria meningitidis strain M07162]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATATTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1KW94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

99.329

100

0.993
  comP Neisseria meningitidis 8013

98.658

100

0.987
  comP Neisseria subflava NJ9703

48.98

98.658

0.483

Multiple sequence alignment