Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6A11_RS07945 Genome accession   NZ_CP016605
Coordinates   1721157..1722377 (-) Length   406 a.a.
NCBI ID   WP_132023670.1    Uniprot ID   A0A4V2SJ44
Organism   Bisgaardia hudsonensis strain M327/99/2     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1708061..1744953 1721157..1722377 within 0


Gene organization within MGE regions


Location: 1708061..1744953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6A11_RS07880 (A6A11_07780) - 1708219..1709577 (-) 1359 WP_132023696.1 Na+/H+ antiporter family protein -
  A6A11_RS07885 (A6A11_07785) rnt 1709630..1710283 (-) 654 WP_132023648.1 ribonuclease T -
  A6A11_RS07890 (A6A11_07790) gloA 1710397..1710804 (-) 408 WP_132023650.1 lactoylglutathione lyase -
  A6A11_RS07895 (A6A11_07795) - 1711045..1712535 (+) 1491 WP_132023652.1 SulP family inorganic anion transporter -
  A6A11_RS07900 (A6A11_07800) - 1712608..1712874 (-) 267 WP_132023654.1 helix-turn-helix domain-containing protein -
  A6A11_RS07905 (A6A11_07805) - 1713010..1713732 (+) 723 WP_132023656.1 DUF3944 domain-containing protein -
  A6A11_RS07910 - 1713828..1714010 (-) 183 Protein_1524 DUF1698 domain-containing protein -
  A6A11_RS07915 (A6A11_07810) glpQ 1714448..1715536 (-) 1089 WP_132023658.1 glycerophosphodiester phosphodiesterase -
  A6A11_RS07920 (A6A11_07815) glpT 1715608..1717050 (-) 1443 WP_132023660.1 glycerol-3-phosphate transporter -
  A6A11_RS07925 (A6A11_07820) - 1717105..1718661 (-) 1557 WP_132023662.1 glycerol-3-phosphate dehydrogenase/oxidase -
  A6A11_RS07930 (A6A11_07825) - 1718987..1719745 (-) 759 WP_132023664.1 DeoR/GlpR family transcriptional regulator -
  A6A11_RS07935 (A6A11_07830) coaE 1719779..1720396 (-) 618 WP_132023666.1 dephospho-CoA kinase -
  A6A11_RS07940 (A6A11_07835) - 1720441..1721157 (-) 717 WP_165906476.1 A24 family peptidase -
  A6A11_RS07945 (A6A11_07840) pilC 1721157..1722377 (-) 1221 WP_132023670.1 type II secretion system F family protein Machinery gene
  A6A11_RS07950 (A6A11_07845) pilB 1722379..1723818 (-) 1440 WP_132023672.1 GspE/PulE family protein Machinery gene
  A6A11_RS07955 (A6A11_07850) pilA 1723839..1724276 (-) 438 WP_132023674.1 prepilin peptidase-dependent pilin Machinery gene
  A6A11_RS07960 (A6A11_07855) ampD 1724408..1724959 (+) 552 WP_132023676.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  A6A11_RS07965 - 1725053..1725226 (-) 174 WP_176672799.1 NF038104 family lipoprotein -
  A6A11_RS07970 (A6A11_07860) ubiD 1725274..1726746 (-) 1473 WP_132023698.1 4-hydroxy-3-polyprenylbenzoate decarboxylase -
  A6A11_RS07975 (A6A11_07865) smpB 1726876..1727355 (+) 480 WP_132023678.1 SsrA-binding protein SmpB -
  A6A11_RS07980 (A6A11_07870) - 1727398..1728963 (+) 1566 WP_132023680.1 class I SAM-dependent methyltransferase -
  A6A11_RS07985 - 1729052..1730373 (+) 1322 Protein_1539 IS3 family transposase -
  A6A11_RS07990 (A6A11_07885) cgtA 1730427..1731599 (-) 1173 WP_132024939.1 Obg family GTPase CgtA -
  A6A11_RS07995 (A6A11_07890) - 1731608..1732528 (-) 921 WP_132024941.1 DMT family transporter -
  A6A11_RS08000 (A6A11_07895) rpmA 1732669..1732926 (-) 258 WP_132024943.1 50S ribosomal protein L27 -
  A6A11_RS08005 (A6A11_07900) rplU 1732947..1733258 (-) 312 WP_132024945.1 50S ribosomal protein L21 -
  A6A11_RS08010 (A6A11_07905) ispB 1733483..1734463 (+) 981 WP_418883941.1 octaprenyl diphosphate synthase -
  A6A11_RS08015 (A6A11_07910) - 1734495..1735202 (+) 708 WP_132024947.1 epoxyqueuosine reductase QueH -
  A6A11_RS08020 (A6A11_07915) parC 1735315..1737561 (-) 2247 WP_132024949.1 DNA topoisomerase IV subunit A -
  A6A11_RS08025 (A6A11_07920) parE 1737662..1739560 (-) 1899 WP_132024951.1 DNA topoisomerase IV subunit B -
  A6A11_RS08030 (A6A11_07925) lpcA 1739773..1740357 (-) 585 WP_132024953.1 D-sedoheptulose 7-phosphate isomerase -
  A6A11_RS08035 (A6A11_07930) mfd 1740462..1743902 (-) 3441 WP_132024955.1 transcription-repair coupling factor -
  A6A11_RS08040 (A6A11_07935) raiA 1744119..1744463 (-) 345 WP_132024957.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46592.50 Da        Isoelectric Point: 9.9996

>NTDB_id=189608 A6A11_RS07945 WP_132023670.1 1721157..1722377(-) (pilC) [Bisgaardia hudsonensis strain M327/99/2]
MSDLKLYQWKATNRLQQKQKGKLVAKNENIARQILFQKGMQQIRLQRNWQFSFNPKSTEICDLLTQLAILLKSSVPLKQS
LNLLMQNCTNIALNAWLRNLLTDIENGFSFSQSLEKQGKYLNYQECQLIYVGEMTGKLTEICQQISVHRQQSLVLQRKIQ
KILLYPVMVLAISVVITTLLLIFIVPKFSEMYMDKQVDLPAFTNLLLILSEVLQQYILHIGLLVIIGVMLIRFRLQRSIW
LNKQKDRLVSFIPILNNIAMLSRLVNFCRSLSLMINSGIPLKQGLQSFLPKPKIWQVSAKIQGDLWLQTEVKSILNWINQ
GYAFSDSVGSNLFTMEAQQMLQVGEKSGELALVLEYIAENNKQKLDHQIDLLSQMLEPLLMVIIGGIIGMIMLGMYLPIF
NMGSLI

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=189608 A6A11_RS07945 WP_132023670.1 1721157..1722377(-) (pilC) [Bisgaardia hudsonensis strain M327/99/2]
ATGTCAGATTTAAAACTGTACCAATGGAAAGCCACAAATCGTTTACAACAAAAACAAAAAGGAAAGTTAGTTGCTAAAAA
TGAGAATATTGCTCGGCAAATTTTATTCCAGAAAGGAATGCAACAGATAAGATTACAACGAAATTGGCAATTTAGTTTTA
ACCCTAAAAGTACGGAGATTTGTGATTTGCTTACGCAACTGGCTATTCTATTAAAATCTTCTGTGCCTTTAAAGCAGAGT
TTGAATTTACTTATGCAGAATTGTACTAATATTGCTTTGAATGCGTGGCTAAGGAATTTATTAACAGATATTGAAAATGG
TTTTTCATTTTCACAAAGTTTAGAGAAACAAGGGAAATATTTAAATTATCAAGAGTGTCAATTAATCTATGTGGGAGAGA
TGACAGGAAAATTGACAGAAATATGCCAACAAATTTCAGTACATCGTCAACAATCTTTAGTACTGCAACGTAAAATTCAG
AAAATTTTATTATATCCAGTAATGGTATTAGCCATTTCGGTAGTTATTACCACTTTATTATTGATTTTTATTGTGCCTAA
ATTCTCGGAAATGTATATGGATAAGCAAGTGGATTTACCTGCTTTTACAAATTTACTACTTATCTTATCTGAAGTATTAC
AACAATATATTCTTCATATCGGTTTATTAGTTATTATAGGTGTTATGCTTATTCGTTTTCGATTACAACGATCTATTTGG
TTAAATAAGCAAAAAGATCGTTTAGTTTCATTCATTCCTATTTTAAATAATATTGCAATGCTTTCTCGATTAGTCAATTT
TTGTCGTAGTTTATCTTTGATGATTAACTCCGGTATTCCTTTAAAACAAGGGTTACAATCTTTTTTACCAAAACCGAAAA
TATGGCAGGTGTCTGCAAAAATACAAGGTGATTTATGGTTACAAACAGAAGTTAAATCAATACTAAATTGGATAAATCAA
GGTTATGCTTTTTCCGATAGTGTAGGTAGTAATCTATTTACTATGGAGGCTCAACAAATGCTACAGGTTGGTGAAAAAAG
TGGTGAACTTGCTTTAGTCTTAGAATATATTGCAGAAAACAACAAACAAAAATTAGATCATCAGATTGATTTATTATCTC
AAATGTTGGAGCCATTATTAATGGTGATTATTGGGGGGATCATTGGAATGATTATGCTTGGAATGTACTTACCAATATTT
AATATGGGATCATTAATTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V2SJ44

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

55.97

99.015

0.554
  pilC Haemophilus influenzae 86-028NP

55.224

99.015

0.547
  pilC Glaesserella parasuis strain SC1401

40.64

100

0.406

Multiple sequence alignment