Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   B6N50_RS03830 Genome accession   NZ_CP020543
Coordinates   746589..747248 (-) Length   219 a.a.
NCBI ID   WP_081508774.1    Uniprot ID   -
Organism   Escherichia coli C     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 741589..752248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B6N50_RS03805 (B6N50_03805) parE 741680..743572 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  B6N50_RS03810 (B6N50_03810) ygiN 743620..743934 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  B6N50_RS03815 (B6N50_03815) mdaB 743965..744546 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  B6N50_RS03820 (B6N50_03820) ygiZ 744865..745197 (+) 333 WP_000917684.1 DUF2645 family protein -
  B6N50_RS03825 (B6N50_03825) qseC 745243..746592 (-) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  B6N50_RS03830 (B6N50_03830) ciaR 746589..747248 (-) 660 WP_081508774.1 quorum sensing response regulator transcription factor QseB Regulator
  B6N50_RS03835 (B6N50_03835) ygiW 747400..747792 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  B6N50_RS03840 (B6N50_03840) ygiV 747845..748327 (+) 483 WP_000183505.1 AraC family transcriptional regulator -
  B6N50_RS03845 (B6N50_03845) mqsR 748532..748828 (+) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  B6N50_RS03850 (B6N50_03850) mqsA 748830..749225 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  B6N50_RS03855 (B6N50_03855) ygiS 749358..750965 (+) 1608 WP_001295629.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24668.58 Da        Isoelectric Point: 6.7638

>NTDB_id=187410 B6N50_RS03830 WP_081508774.1 746589..747248(-) (ciaR) [Escherichia coli C]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPHKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=187410 B6N50_RS03830 WP_081508774.1 746589..747248(-) (ciaR) [Escherichia coli C]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCACAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365