Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A9P13_RS02120 Genome accession   NZ_CP020516
Coordinates   440544..441176 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 222     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 435544..446176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A9P13_RS02095 (A9P13_02115) yhfG 435676..435843 (+) 168 WP_000736860.1 YhfG family protein -
  A9P13_RS02100 (A9P13_02120) fic 435833..436435 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  A9P13_RS02105 (A9P13_02125) pabA 436467..437030 (+) 564 WP_001521451.1 aminodeoxychorismate synthase component 2 -
  A9P13_RS02110 (A9P13_02130) argD 437116..438336 (+) 1221 WP_000963771.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A9P13_RS02115 (A9P13_02135) yhfK 438403..440493 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  A9P13_RS02120 (A9P13_02140) crp 440544..441176 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A9P13_RS02130 (A9P13_02150) yhfA 441478..441882 (+) 405 WP_001148908.1 OsmC family protein -
  A9P13_RS02135 (A9P13_02155) prkB 441937..442806 (-) 870 WP_001274680.1 phosphoribulokinase -
  A9P13_RS02140 (A9P13_02160) yheU 442860..443078 (-) 219 WP_000907085.1 YheU family protein -
  A9P13_RS02145 (A9P13_02165) yheT 443072..444094 (-) 1023 WP_001521449.1 hydrolase -
  A9P13_RS02150 (A9P13_02170) yheS 444094..446007 (-) 1914 WP_020232893.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=187236 A9P13_RS02120 WP_000242755.1 440544..441176(-) (crp) [Escherichia coli strain 222]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=187236 A9P13_RS02120 WP_000242755.1 440544..441176(-) (crp) [Escherichia coli strain 222]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGCCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATAGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467