Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A9P12_RS02225 Genome accession   NZ_CP020514
Coordinates   443840..444472 (-) Length   210 a.a.
NCBI ID   WP_000242761.1    Uniprot ID   -
Organism   Escherichia coli strain 219     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 438840..449472
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A9P12_RS02200 (A9P12_02225) yhfG 438972..439139 (+) 168 WP_000736862.1 YhfG family protein -
  A9P12_RS02205 (A9P12_02230) fic 439129..439731 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  A9P12_RS02210 (A9P12_02235) pabA 439763..440326 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  A9P12_RS02215 (A9P12_02240) argD 440412..441632 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A9P12_RS02220 (A9P12_02245) yhfK 441699..443789 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  A9P12_RS02225 (A9P12_02250) crp 443840..444472 (-) 633 WP_000242761.1 cAMP-activated global transcriptional regulator CRP Regulator
  A9P12_RS02235 (A9P12_02260) yhfA 444774..445178 (+) 405 WP_001148908.1 OsmC family protein -
  A9P12_RS02240 (A9P12_02265) prkB 445233..446102 (-) 870 WP_001274680.1 phosphoribulokinase -
  A9P12_RS02245 (A9P12_02270) yheU 446156..446374 (-) 219 WP_000907085.1 YheU family protein -
  A9P12_RS02250 (A9P12_02275) yheT 446368..447390 (-) 1023 WP_000057356.1 hydrolase -
  A9P12_RS02255 (A9P12_02280) yheS 447390..449303 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23644.41 Da        Isoelectric Point: 8.2710

>NTDB_id=187153 A9P12_RS02225 WP_000242761.1 443840..444472(-) (crp) [Escherichia coli strain 219]
MVLGKTQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=187153 A9P12_RS02225 WP_000242761.1 443840..444472(-) (crp) [Escherichia coli strain 219]
ATGGTGCTTGGCAAAACGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.238

100

0.952
  crp Haemophilus influenzae Rd KW20

78.049

97.619

0.762
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467