Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   A6J87_RS04475 Genome accession   NZ_CP020451
Coordinates   897616..899553 (-) Length   645 a.a.
NCBI ID   WP_080611621.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 892616..904553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS04445 (A6J87_04425) spx 892844..893242 (-) 399 WP_002886328.1 transcriptional regulator Spx -
  A6J87_RS04450 (A6J87_04430) recA 893411..894550 (-) 1140 WP_002889600.1 recombinase RecA Machinery gene
  A6J87_RS04455 (A6J87_04435) cinA 894591..895856 (-) 1266 WP_070575131.1 competence/damage-inducible protein A Machinery gene
  A6J87_RS04460 (A6J87_04440) - 895953..896507 (-) 555 WP_080611618.1 DNA-3-methyladenine glycosylase I -
  A6J87_RS04465 (A6J87_04445) ruvA 896516..897106 (-) 591 WP_080611619.1 Holliday junction branch migration protein RuvA Machinery gene
  A6J87_RS04470 (A6J87_04450) - 897264..897485 (-) 222 WP_037597288.1 hypothetical protein -
  A6J87_RS04475 (A6J87_04455) hexB 897616..899553 (-) 1938 WP_080611621.1 DNA mismatch repair endonuclease MutL Machinery gene
  A6J87_RS04480 (A6J87_04460) - 899605..899910 (-) 306 WP_070575143.1 hypothetical protein -
  A6J87_RS04485 (A6J87_04465) - 900089..900526 (+) 438 WP_037599421.1 LytTR family DNA-binding domain-containing protein -
  A6J87_RS04490 (A6J87_04470) - 900523..900978 (+) 456 WP_037599423.1 DUF3021 domain-containing protein -
  A6J87_RS04495 (A6J87_04475) hexA 901012..903570 (-) 2559 WP_037599425.1 DNA mismatch repair protein MutS Machinery gene
  A6J87_RS04500 (A6J87_04480) - 903563..903922 (-) 360 WP_080611622.1 YlbF family regulator -
  A6J87_RS04505 (A6J87_04485) argR 903922..904350 (-) 429 WP_192573915.1 arginine repressor -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72398.55 Da        Isoelectric Point: 5.3693

>NTDB_id=186743 A6J87_RS04475 WP_080611621.1 897616..899553(-) (hexB) [Streptococcus salivarius strain FDAARGOS_259]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEIEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGATKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSESPVSSVENKPQP
SVKQAQRSVDESDDKHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKYEY
YREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMPLLNQVGIYLEPYGNNTFILREHPIWMKEEEIETAVYEMCDMLLL
TNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTSLR
DLGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=186743 A6J87_RS04475 WP_080611621.1 897616..899553(-) (hexB) [Streptococcus salivarius strain FDAARGOS_259]
ATGCCAAAAATCATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGAGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTGGTGGAAAATGCTATTGATGCAGGTAGCACCCAGATTACCATTGAAATTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGTGAAGGAATGGCTCAAGCTGACGTAGCCATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGACCTCTTTCGTATTCGAACTCTTGGTTTTCGAGGTGAGGCCCTGCCATCAATAGCTTCTATCAG
TCATCTTACCATTGTGACGGCGGCTGATGGAGAAGCCTATGGGACTAAACTGGTTGCCAAAGGTGGGGAAATTGAGAGTC
AGGATCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAATTTATTTTATAACACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTGAGTCTAGCTCATCCTGAGGTTGCCTT
CACCTTGCTTAATGACGGTCGTCAGTTGACACAGACCTCAGGTACTGGAGACCTCCGTCAAGCTATTGCCGGGATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAAATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGCTATGTCAGCCTTCCT
GAATTAACTCGTGCGAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATAAAAAACTTTCTACTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTCATGGTGGGACGCTTCCCAATTGCGGTTATTGATATTCAGATTGATCCTTATT
TGGCTGATGTCAATGTTCACCCAACAAAGCAGGAAGTACGTATCTCTAAAGAAAAAGAGCTCATGGCTCTTATCAGCTCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACTAGAGGTGC
AACTAAGCCGGTTCAAACGAGTTTACCACTCAAACAGACCAATCTTTACTATGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCACTCGTATCAGAGTCCCCAGTTTCATCGGTAGAAAACAAACCGCAACCT
TCTGTTAAACAGGCACAACGTTCAGTAGATGAAAGTGATGACAAACACGAAAAACTCGACTATAAAAACAAGTCGAAAAT
GAAGCGCATGCTTGAAACTCTAGATAATGAGGAAACATCAACCTTCCCTGAATTGGAGTTTTTTGGTCAAATGCATGGAA
CCTATCTCTTTGCGCAAGGACAAGGCGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTATGAGTAC
TATCGTGAAAAGATCGGTGAGGTTGACAGCAGTTTACAACAGCTCTTGGTTCCCTATCTCTTTGAATTTTCAGGTTCAGA
TTACATTAGTTTACAAGAAAAAATGCCCCTTCTTAACCAGGTTGGTATCTATCTAGAGCCTTATGGGAATAACACCTTCA
TTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAAACTGCAGTCTATGAGATGTGCGACATGCTTCTTTTG
ACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTAGCCATCATGATGAGTTGTAAACGTTCAATCAAGGCCAATCA
TGCTCTTGATGATTACTCTGCGCGTGACCTCCTAGTGCAGCTTGCACAGTGTAAAAACCCCTACAATTGCCCTCACGGAC
GTCCTGTACTTGTCAACTTTACAAAGTCTGATATGGAAAAAATGTTCCGCCGAATTCAAGAAAATCATACCAGTCTACGT
GACTTAGGAAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(446-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.817

100

0.71