Detailed information NTG0186744

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: A6J87_RS04495
• Genome accession: NZ_CP020451
• Coordinates: 901012..903570 (-)
• Length: 852 a.a.
• NCBI ID: WP_037599425.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_259
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 896012..908570

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J87_RS04465 (A6J87_04445)	ruvA	896516..897106 (-)	591	WP_080611619.1	Holliday junction branch migration protein RuvA	Machinery gene
A6J87_RS04470 (A6J87_04450)	-	897264..897485 (-)	222	WP_037597288.1	hypothetical protein	-
A6J87_RS04475 (A6J87_04455)	hexB	897616..899553 (-)	1938	WP_080611621.1	DNA mismatch repair endonuclease MutL	Machinery gene
A6J87_RS04480 (A6J87_04460)	-	899605..899910 (-)	306	WP_070575143.1	hypothetical protein	-
A6J87_RS04485 (A6J87_04465)	-	900089..900526 (+)	438	WP_037599421.1	LytTR family DNA-binding domain-containing protein	-
A6J87_RS04490 (A6J87_04470)	-	900523..900978 (+)	456	WP_037599423.1	DUF3021 domain-containing protein	-
A6J87_RS04495 (A6J87_04475)	hexA	901012..903570 (-)	2559	WP_037599425.1	DNA mismatch repair protein MutS	Machinery gene
A6J87_RS04500 (A6J87_04480)	-	903563..903922 (-)	360	WP_080611622.1	YlbF family regulator	-
A6J87_RS04505 (A6J87_04485)	argR	903922..904350 (-)	429	WP_192573915.1	arginine repressor	-
A6J87_RS04510 (A6J87_04490)	argS	904505..906196 (+)	1692	WP_080611625.1	arginine--tRNA ligase	-
A6J87_RS04515 (A6J87_04495)	purB	907073..908371 (-)	1299	WP_080611627.1	adenylosuccinate lyase	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95682.90 Da
• Isoelectric Point: 4.6570

>NTDB_id=186744 A6J87_RS04495 WP_037599425.1 901012..903570(-) (hexA) [Streptococcus salivarius strain FDAARGOS_259]
MAKEKISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKVGSRFGLAYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLPEVDEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQTTITERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDDALSRLLQELDALPELESLIRSAIDP
DAPATITEGGIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQFLAKAIATVDVLQSLAVTAETNHYVRPVFN
DEHRIVIDQGRHAVVEKVMGVQEYIPNTITFDSQTNIQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNNLTHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGDTVTIQPQEKVSPQ
EKPATETHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=186744 A6J87_RS04495 WP_037599425.1 901012..903570(-) (hexA) [Streptococcus salivarius strain FDAARGOS_259]
ATGGCTAAGGAAAAAATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTGTT
TCGGATGGGGGATTTTTACGAATTATTTTACGATGATGCCGTTAAGGCTGCTCAAATTTTGGAAATTAGCCTAACCAGTC
GTAATAAGAACGCAGATAATCCCATTCCTATGGCAGGTGTTCCTTATCATTCGGCTCAAGCCTATATTGATGTCTTGGTT
GAGATGGGCTACAAAGTAGCCATTGCTGAGCAGATGGAGGACCCTAAACAGGCTGTTGGCGTGGTTAAGCGTGAGGTAGT
TCAGGTTATCACGCCAGGGACAGTGGTTGACAGCTCTAAACCTGATAATGCCAACAATTTCTTAGTAGCCATTGACAAGG
TTGGAAGTCGATTCGGCCTGGCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGATGATTTCAGTTCA
GTTTGTAGTGAAATTCAGAACCTTAAGGCACGTGAAGTAGTCGTTGGGTATGATTTACCTGAAGTTGACGAACAAGTTTT
GGTCAAGCAACTCAACCTTCTACTCTCCAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAG
ATTTGGAAAGCAGTGTGGCTGGTAAACTTCTCCAGTATGTGCACCGTACTCAGATGCGTGAGCTCAGTCATTTACAAAAG
GCTCAGCACTATGAGATTAAGGATTACCTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTACTAGAAAATGCTAG
AACGGGCAAGAAACACGGATCTCTTTTCTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGAACTT
GGATTGATCGTCCTTTAGTGAATCAAACCACTATCACCGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTT
GAGCGGAGTGACTTGACTGAGAGTCTAAAAGGTGTTTACGATATTGAACGCCTGGCCAGTCGTGTTTCCTTTGGCAAGGC
TAATCCAAAAGATTTGATTCAGCTAGGTCATACTTTGGCTCAAGTACCGGTGATTAAGGCGATTTTGGAGTCTTTTAATG
ACGATGCCTTGTCACGTCTTTTACAAGAGTTAGATGCTCTGCCAGAATTAGAGAGTTTGATTCGGTCGGCTATTGATCCT
GATGCCCCTGCAACCATTACAGAAGGTGGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGAT
GAGTGAGGGAACCTCATGGATCGCAGATATCGAAGCTAAAGAACGTGAAGCGTCTGGTATTACAACACTAAAGATTGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGAAAGGCA
ACTCTGAAAAATTCAGAGCGCTTTGGAACTGCTGAGTTGGCTAAAATTGAAGGTGAGATGCTTGAGGCGCGTGAAAAATC
ATCAACGCTGGAATATGATATTTTCATGCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATTTTTGGCTA
AGGCTATTGCGACAGTCGATGTGCTTCAGAGTTTGGCTGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAAT
GATGAGCATCGTATCGTTATTGATCAAGGTCGTCATGCGGTGGTTGAGAAGGTTATGGGCGTTCAAGAATACATTCCAAA
CACCATTACCTTTGACAGTCAGACCAATATTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCCACCTATATGCGTC
AGTTAGCCTTGTCAGTAGTTATGGCTCAGATGGGGTCTTACGTGCCAGCAGATAGTATTGACTTGCCAGTTTTTGATGCT
ATCTATACACGTATTGGTGCTGCAGATGACCTGATTTCAGGGCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAACCA
GGCTATTAAGCGGGCGACACCTAATTCCTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCCACTTATGATGGTATGG
CTCTGGCCCAGTCTATTATTGAGTTTATTCATGACAAGGTGGGGGCTAAGACCATGTTTGCTACCCATTATCATGAGTTG
ACAGCCCTGTCAAACAATTTGACACACCTTGTCAACGTTCATGTGGCGACACTTGAAAAGGATGGTGAGGTGACTTTCCT
TCACAAGATTGTTGATGGCCCAGCTGACAAATCTTATGGTATTCATGTGGCTAAGATTGCAGGTTTACCAGCAGATTTAC
TGGAACGTGCTGACACCATCTTGACACAACTAGAGGGCGATACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAA
GAGAAGCCTGCCACTGAAACGCATGTCAACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGA
GTTACGTGATTTAGATATTTACAACATGACACCTATGCAAGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.178	100	0.742
mutS	Pseudomonas stutzeri strain ATCC 17587	35.954	100	0.365