Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A6J72_RS03180 Genome accession   NZ_CP020433
Coordinates   643291..643923 (-) Length   210 a.a.
NCBI ID   WP_082311762.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 638291..648923
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS03150 (A6J72_03145) - 638663..639439 (+) 777 WP_105255917.1 aminoglycoside 3'-phosphotransferase -
  A6J72_RS03155 (A6J72_03150) recX 639504..640280 (+) 777 WP_082311760.1 recombination regulator RecX Regulator
  A6J72_RS03160 (A6J72_03155) - 640367..640900 (+) 534 WP_082311761.1 DUF402 domain-containing protein -
  A6J72_RS03165 (A6J72_03160) - 641020..641337 (+) 318 WP_009568141.1 DUF960 domain-containing protein -
  A6J72_RS03170 (A6J72_03165) - 641457..641849 (-) 393 WP_014829583.1 S1 RNA-binding domain-containing protein -
  A6J72_RS03175 (A6J72_03170) - 641851..643251 (-) 1401 WP_102570638.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  A6J72_RS03180 (A6J72_03175) vraR 643291..643923 (-) 633 WP_082311762.1 response regulator transcription factor Regulator
  A6J72_RS03185 (A6J72_03180) - 643925..644920 (-) 996 WP_082311763.1 sensor histidine kinase -
  A6J72_RS03190 (A6J72_03185) liaF 644917..645615 (-) 699 WP_082311764.1 cell wall-active antibiotics response protein LiaF -
  A6J72_RS03195 (A6J72_03190) stkP 645878..647752 (-) 1875 WP_003073669.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A6J72_RS03200 (A6J72_03195) - 647749..648489 (-) 741 WP_003073671.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23743.44 Da        Isoelectric Point: 4.7982

>NTDB_id=186400 A6J72_RS03180 WP_082311762.1 643291..643923(-) (vraR) [Streptococcus intermedius strain FDAARGOS_233]
MQILLVDDHEMVRLGLKSYLDVQDDVDMVVEASNGCEGMEKALSLRPDVIMMDIVMPKMNGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEELTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=186400 A6J72_RS03180 WP_082311762.1 643291..643923(-) (vraR) [Streptococcus intermedius strain FDAARGOS_233]
ATGCAGATTTTATTAGTAGATGATCATGAAATGGTGCGACTTGGTTTGAAGAGCTATTTGGATGTACAAGATGATGTTGA
TATGGTGGTAGAAGCTTCAAATGGTTGTGAAGGGATGGAAAAGGCTCTGTCATTACGGCCAGATGTGATAATGATGGATA
TTGTCATGCCTAAAATGAATGGGATCGAAGCTACACTTGCTATTTTAAAAGAATGGCCTGAAGCTAAAATTCTTATTTTG
ACTTCTTATTTAGATAATGAAAAAATTTACCCAGTTTTAGATGCAGGGGCTAAAGGATACATGCTTAAAACATCTAGTGC
TGACGATATCTTACGAGCAGTTCGAAAGGTAGCCAAGGGTGAACTGGCTATTGAAACAGAGGTCAGTCAGAAAGTGGAAT
ACCATCGAAATCATATTGAATTACATGAAGAGCTAACAGCGCGTGAGCGCGATATTTTAGGTCTATTAGCAAAAGGGTAT
GAAAATCAACGGATAGCAGATGAGTTGTTTATTTCGTTGAAGACTGTTAAAACACATGTATCTAATATCTTATCAAAATT
AGAAGTAAGTGATCGGACACAAGCTGTTGTTTACGCCTTTCAGCACCACCTTGTCCCACAAGATGACATTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414