Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   A6J72_RS01150 Genome accession   NZ_CP020433
Coordinates   217674..219020 (-) Length   448 a.a.
NCBI ID   WP_082311553.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 212674..224020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS01125 (A6J72_01125) - 212897..213490 (-) 594 WP_020998684.1 class I SAM-dependent methyltransferase -
  A6J72_RS01130 (A6J72_01130) coaA 213583..214503 (+) 921 WP_021002770.1 type I pantothenate kinase -
  A6J72_RS01135 (A6J72_01135) rpsT 214572..214808 (+) 237 WP_003072853.1 30S ribosomal protein S20 -
  A6J72_RS01140 (A6J72_01140) - 214873..215382 (+) 510 WP_021002771.1 DNA topology modulation protein -
  A6J72_RS01145 (A6J72_01145) - 215789..217237 (+) 1449 WP_082311552.1 alpha-amylase -
  A6J72_RS01150 (A6J72_01150) ciaH 217674..219020 (-) 1347 WP_082311553.1 cell wall metabolism sensor histidine kinase WalK Regulator
  A6J72_RS01155 (A6J72_01155) ciaR 219010..219684 (-) 675 WP_003036714.1 response regulator transcription factor Regulator
  A6J72_RS01160 (A6J72_01160) - 219946..220389 (-) 444 WP_082311554.1 hypothetical protein -
  A6J72_RS09625 - 220688..220864 (-) 177 WP_125873248.1 alpha/beta hydrolase -
  A6J72_RS01165 (A6J72_01165) - 220954..221427 (-) 474 WP_082311555.1 alpha/beta fold hydrolase -
  A6J72_RS01175 (A6J72_01175) rplS 221672..222019 (-) 348 WP_003024326.1 50S ribosomal protein L19 -
  A6J72_RS01180 (A6J72_01180) - 222169..223128 (-) 960 WP_021002774.1 ROK family glucokinase -

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 50922.71 Da        Isoelectric Point: 10.1689

>NTDB_id=186376 A6J72_RS01150 WP_082311553.1 217674..219020(-) (ciaH) [Streptococcus intermedius strain FDAARGOS_233]
MLNKLKKAWYADDFSYFIRNFGIFTLIFSAMTLIIIQVMRSSLYTTVDNNLKSLSQDSASVINLALARKVGLEQKSENGE
PKSGTADKELTDKPNVSANTEVILFDKNYKSIITSNNFLGFNKLSFNSKQLDRIRQIQVKSNYGREETYRMVLFQVKLPN
LETNVKYAAVFINISQLEQTSQNHEQLIVVVMISFWGISLIASVYLARVSVKPLLESIQKQKSFVENASHELRTPLAVLQ
NRLETLFRKPEATIMESSESIASSLDEVRNMKMLTTNLLNLARRDDGIKPEIGDIEPNFFNTTFTNYEMVATENGKVFRF
DNRIHRVIKTDKTLLKQLMTILFDNALKYTDEDGVIELTISANDRNLFLKVSDNGPGISTADKKKIFDRFYRVDKARTRQ
TGGFGLGLSLAKQITEALKGTIVVKDNKPKGTIFEVKIAIRTDNKKKK

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=186376 A6J72_RS01150 WP_082311553.1 217674..219020(-) (ciaH) [Streptococcus intermedius strain FDAARGOS_233]
ATGCTGAATAAACTAAAAAAAGCATGGTATGCGGATGATTTTTCTTATTTCATTCGCAATTTTGGTATTTTTACTCTCAT
TTTCTCAGCTATGACCTTGATTATCATTCAAGTTATGCGCTCAAGCCTTTATACAACGGTAGATAATAATTTAAAAAGCT
TGAGTCAAGATTCGGCTTCTGTGATTAATTTAGCGCTTGCTCGAAAAGTAGGGCTAGAGCAAAAGTCAGAAAATGGAGAA
CCTAAAAGTGGAACAGCTGACAAAGAGCTGACAGATAAACCAAATGTGAGTGCCAATACAGAAGTTATTTTATTTGATAA
GAATTATAAATCAATTATTACAAGCAATAATTTTTTAGGGTTTAATAAACTTTCCTTTAATAGCAAGCAATTAGATCGTA
TTCGTCAAATTCAAGTAAAAAGCAATTACGGCCGAGAAGAAACCTATCGGATGGTTTTGTTTCAAGTGAAATTGCCTAAT
TTAGAAACCAATGTCAAATACGCAGCAGTTTTTATCAATATTAGCCAATTGGAACAAACTAGTCAAAACCATGAACAGTT
GATTGTAGTTGTGATGATTAGTTTCTGGGGAATTTCCTTGATTGCTAGTGTCTATCTTGCACGAGTAAGTGTCAAACCGC
TTTTGGAAAGTATTCAAAAACAAAAGAGCTTTGTCGAAAATGCTAGTCATGAATTACGCACACCTTTAGCCGTTTTGCAA
AATCGTTTGGAGACTTTGTTTAGAAAACCAGAAGCTACCATTATGGAATCGAGTGAAAGCATCGCTTCTAGTTTAGATGA
AGTGCGAAACATGAAAATGTTGACAACGAACTTACTTAATTTAGCACGGCGTGATGATGGGATTAAACCAGAGATTGGTG
ATATTGAACCCAATTTCTTTAATACGACCTTTACGAACTATGAAATGGTTGCCACAGAAAATGGAAAAGTTTTTCGATTT
GACAATAGGATTCACCGTGTGATAAAAACGGATAAAACCTTACTGAAGCAATTGATGACTATCTTGTTTGATAATGCCCT
GAAATATACAGACGAAGATGGTGTGATTGAATTAACAATCTCTGCAAATGATCGAAATTTGTTTTTGAAGGTTTCGGATA
ATGGTCCAGGGATTAGTACAGCAGATAAGAAAAAGATTTTTGATCGTTTTTATCGTGTTGATAAAGCACGGACTCGACAG
ACAGGTGGTTTTGGTTTAGGGTTGTCACTTGCAAAGCAAATCACAGAAGCTCTTAAAGGAACCATTGTAGTGAAAGACAA
TAAGCCTAAAGGAACTATTTTTGAGGTGAAGATTGCGATTCGAACGGATAATAAAAAGAAAAAATAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(331-438)

His Kinase A (phospho-acceptor) domain (HisKA)

(222-287)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

70.312

100

0.703
  ciaH Streptococcus pneumoniae D39

70.312

100

0.703
  ciaH Streptococcus pneumoniae R6

70.312

100

0.703
  ciaH Streptococcus pneumoniae TIGR4

70.312

100

0.703
  ciaH Streptococcus mutans UA159

55.708

97.768

0.545