Detailed information NTG0186280

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: A9P90_RS09290
• Genome accession: NZ_CP016214
• Coordinates: 2015228..2016565 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PA121617
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 2010228..2021565

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A9P90_RS09265 (A9P90_09265)	pgeF	2010371..2011099 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
A9P90_RS09270 (A9P90_09270)	rluD	2011096..2012058 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
A9P90_RS09275 (A9P90_09275)	-	2012204..2013229 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
A9P90_RS09280 (A9P90_09280)	-	2013386..2013631 (+)	246	WP_003102591.1	PP0621 family protein	-
A9P90_RS09285 (A9P90_09285)	pilS	2013621..2015213 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
A9P90_RS09290 (A9P90_09290)	pilR	2015228..2016565 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
A9P90_RS09295 (A9P90_09295)	thiO	2016611..2017705 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
A9P90_RS09300 (A9P90_09300)	-	2017840..2018349 (+)	510	WP_003102595.1	GspH/FimT family pseudopilin	-
A9P90_RS09305 (A9P90_09305)	-	2018455..2018961 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
A9P90_RS09310 (A9P90_09310)	pilV	2018952..2019509 (+)	558	WP_003102600.1	type 4a pilus minor pilin PilV	Machinery gene
A9P90_RS09315 (A9P90_09315)	pilW	2019506..2020330 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
A9P90_RS09320 (A9P90_09320)	pilX	2020327..2020914 (+)	588	WP_003102605.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=186280 A9P90_RS09290 WP_003094694.1 2015228..2016565(+) (pilR) [Pseudomonas aeruginosa strain PA121617]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=186280 A9P90_RS09290 WP_003094694.1 2015228..2016565(+) (pilR) [Pseudomonas aeruginosa strain PA121617]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384