Detailed information NTG0185411

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: A9497_RS09305
• Genome accession: NZ_CP016026
• Coordinates: 1767018..1768019 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain KLDS SM
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1762018..1773019

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A9497_RS09285 (A9497_09285)	smpB	1763125..1763589 (+)	465	WP_064784301.1	SsrA-binding protein SmpB	-
A9497_RS09290 (A9497_09290)	-	1763743..1765149 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
A9497_RS09295 (A9497_09295)	-	1765151..1765516 (+)	366	WP_064784304.1	S1 RNA-binding domain-containing protein	-
A9497_RS09300 (A9497_09300)	-	1765619..1766704 (-)	1086	WP_011680935.1	M24 family metallopeptidase	-
A9497_RS09305 (A9497_09305)	ccpA	1767018..1768019 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
A9497_RS10545	-	1768078..1768275 (+)	198	WP_014608125.1	hypothetical protein	-
A9497_RS11520	-	1768381..1768605 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
A9497_RS09310 (A9497_09310)	-	1768606..1769145 (+)	540	WP_011680936.1	MmcQ/YjbR family DNA-binding protein	-
A9497_RS09315 (A9497_09315)	-	1769158..1770273 (+)	1116	WP_011680937.1	glycerate kinase	-
A9497_RS09320 (A9497_09320)	-	1770320..1770775 (-)	456	WP_011680938.1	YueI family protein	-
A9497_RS09325 (A9497_09325)	eno	1770984..1772288 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
A9497_RS09330 (A9497_09330)	-	1772440..1772625 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=185411 A9497_RS09305 WP_004197422.1 1767018..1768019(+) (ccpA) [Streptococcus thermophilus strain KLDS SM]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=185411 A9497_RS09305 WP_004197422.1 1767018..1768019(+) (ccpA) [Streptococcus thermophilus strain KLDS SM]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547