Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EC767_RS24080 Genome accession   NZ_CP020107
Coordinates   4604064..4604696 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 13E0767     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4599064..4609696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EC767_RS24050 (EC767_24055) yheS 4599233..4601146 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  EC767_RS24055 (EC767_24060) yheT 4601146..4602168 (+) 1023 WP_000057405.1 hydrolase -
  EC767_RS24060 (EC767_24065) yheU 4602162..4602380 (+) 219 WP_000907085.1 YheU family protein -
  EC767_RS24065 (EC767_24070) prkB 4602434..4603303 (+) 870 WP_001274684.1 phosphoribulokinase -
  EC767_RS24070 (EC767_24075) yhfA 4603358..4603762 (-) 405 WP_001148908.1 OsmC family protein -
  EC767_RS24080 (EC767_24085) crp 4604064..4604696 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EC767_RS24085 (EC767_24090) yhfK 4604747..4606837 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  EC767_RS24090 (EC767_24095) argD 4606904..4608124 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EC767_RS24095 (EC767_24100) pabA 4608210..4608773 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  EC767_RS24100 (EC767_24105) fic 4608805..4609407 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  EC767_RS24105 (EC767_24110) yhfG 4609397..4609564 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=185083 EC767_RS24080 WP_000242755.1 4604064..4604696(+) (crp) [Escherichia coli strain 13E0767]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=185083 EC767_RS24080 WP_000242755.1 4604064..4604696(+) (crp) [Escherichia coli strain 13E0767]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467