Detailed information NTG0184897

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: A8O17_RS12380
• Genome accession: NZ_CP015975
• Coordinates: 2346916..2347533 (-)
• Length: 205 a.a.
• NCBI ID: WP_004398514.1
• Uniprot ID: A0AAE2SLR2
• Organism: Bacillus subtilis subsp. subtilis strain delta6
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2341916..2352533

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A8O17_RS12355 (A8O17_12355)	rpsT	2342218..2342484 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
A8O17_RS12360 (A8O17_12360)	holA	2342499..2343542 (-)	1044	WP_003229987.1	DNA polymerase III subunit delta	-
A8O17_RS20900	-	2343582..2343731 (-)	150	WP_003229985.1	hypothetical protein	-
A8O17_RS12365 (A8O17_12365)	yqzM	2343772..2343906 (+)	135	WP_003229983.1	YqzM family protein	-
A8O17_RS12370 (A8O17_12370)	comEC	2343946..2346276 (-)	2331	WP_009967776.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
A8O17_RS12375 (A8O17_12375)	comEB	2346280..2346849 (-)	570	WP_003229978.1	ComE operon protein 2	-
A8O17_RS12380 (A8O17_12380)	comEA	2346916..2347533 (-)	618	WP_004398514.1	competence protein ComEA	Machinery gene
A8O17_RS12385 (A8O17_12385)	comER	2347617..2348438 (+)	822	WP_004398597.1	late competence protein ComER	-
A8O17_RS12390 (A8O17_12390)	yqeM	2348504..2349247 (-)	744	WP_003229973.1	class I SAM-dependent methyltransferase	-
A8O17_RS12395 (A8O17_12395)	rsfS	2349244..2349600 (-)	357	WP_003229971.1	ribosome silencing factor	-
A8O17_RS12400 (A8O17_12400)	yqeK	2349618..2350178 (-)	561	WP_004399059.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
A8O17_RS12405 (A8O17_12405)	nadD	2350168..2350737 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
A8O17_RS12410 (A8O17_12410)	yhbY	2350749..2351039 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
A8O17_RS12415 (A8O17_12415)	aroE	2351033..2351875 (-)	843	WP_003229967.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 21769.45 Da
• Isoelectric Point: 4.7220

>NTDB_id=184897 A8O17_RS12380 WP_004398514.1 2346916..2347533(-) (comEA) [Bacillus subtilis subsp. subtilis strain delta6]
MNWLNQHKKAIILAASAAVFTAIMIFLATGKNKEPVKQAVPTETENTVVKQEANNDESNETIVIDIKGAVQHPGVYEMRT
GDRVSQAIEKAGGTSEQADEAQVNLAEILQDGTVVYIPKKGEETAVQQGGGGSVQSDGGKGALVNINTATLEELQGISGV
GPSKAEAIIAYREENGRFQTIEDITKVSGIGEKSFEKIKSSITVK

Nucleotide

• Length: 618 bp

>NTDB_id=184897 A8O17_RS12380 WP_004398514.1 2346916..2347533(-) (comEA) [Bacillus subtilis subsp. subtilis strain delta6]
ATGAATTGGTTGAATCAGCATAAGAAAGCAATTATTTTAGCGGCTTCTGCGGCTGTTTTCACAGCGATTATGATCTTTCT
GGCCACAGGGAAAAATAAAGAGCCGGTGAAGCAAGCTGTACCAACAGAGACAGAAAATACAGTGGTAAAGCAGGAAGCAA
ACAACGACGAGTCAAACGAAACAATTGTGATAGACATCAAAGGTGCTGTTCAGCATCCTGGCGTTTATGAAATGCGAACA
GGGGACAGAGTATCTCAGGCAATTGAGAAAGCGGGCGGGACCAGTGAACAAGCAGACGAAGCGCAAGTAAATTTGGCGGA
GATTCTGCAGGACGGGACAGTGGTGTACATCCCGAAAAAGGGAGAGGAAACAGCAGTGCAGCAAGGTGGCGGAGGGTCTG
TCCAAAGCGATGGAGGGAAGGGAGCGCTGGTGAATATCAATACAGCAACCTTAGAGGAGTTACAAGGCATCTCAGGGGTG
GGGCCATCCAAAGCTGAAGCTATTATTGCATACCGGGAGGAAAACGGTCGTTTCCAAACAATTGAAGATATCACTAAGGT
TTCAGGAATAGGTGAAAAGTCATTTGAGAAAATAAAGTCTTCCATTACAGTAAAGTGA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (142-203)

• SLBB domain (SLBB) (63-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	100	100	1
comEA	Staphylococcus aureus MW2	37.273	100	0.4
comEA	Staphylococcus aureus N315	36.364	100	0.39