Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EC725_RS02830 Genome accession   NZ_CP020092
Coordinates   562789..563421 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 13E0725     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 557789..568421
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EC725_RS02805 (EC725_02805) yhfG 557921..558088 (+) 168 WP_000736863.1 YhfG family protein -
  EC725_RS02810 (EC725_02810) fic 558078..558680 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  EC725_RS02815 (EC725_02815) pabA 558712..559275 (+) 564 WP_032142035.1 aminodeoxychorismate synthase component 2 -
  EC725_RS02820 (EC725_02820) argD 559361..560581 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EC725_RS02825 (EC725_02825) yhfK 560648..562738 (-) 2091 WP_155120685.1 YccS/YhfK family putative transporter -
  EC725_RS02830 (EC725_02830) crp 562789..563421 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EC725_RS02840 (EC725_02840) yhfA 563723..564127 (+) 405 WP_001148908.1 OsmC family protein -
  EC725_RS02845 (EC725_02845) prkB 564182..565051 (-) 870 WP_001274680.1 phosphoribulokinase -
  EC725_RS02850 (EC725_02850) yheU 565105..565323 (-) 219 WP_000907085.1 YheU family protein -
  EC725_RS02855 (EC725_02855) yheT 565317..566339 (-) 1023 WP_000057352.1 hydrolase -
  EC725_RS02860 (EC725_02860) yheS 566339..568252 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=184718 EC725_RS02830 WP_000242755.1 562789..563421(-) (crp) [Escherichia coli strain 13E0725]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=184718 EC725_RS02830 WP_000242755.1 562789..563421(-) (crp) [Escherichia coli strain 13E0725]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment