Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AM440_RS17285 Genome accession   NZ_CP020058
Coordinates   3388510..3389142 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain AR_0061     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3383510..3394142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM440_RS17260 (AM440_17655) yhfG 3383643..3383810 (+) 168 WP_000736860.1 YhfG family protein -
  AM440_RS17265 (AM440_17660) fic 3383800..3384402 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AM440_RS17270 (AM440_17665) pabA 3384434..3384997 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  AM440_RS17275 (AM440_17670) argD 3385083..3386303 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AM440_RS17280 (AM440_17675) yhfK 3386370..3388460 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AM440_RS17285 (AM440_17680) crp 3388510..3389142 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AM440_RS17295 (AM440_17690) yhfA 3389444..3389848 (+) 405 WP_001148910.1 OsmC family protein -
  AM440_RS17300 (AM440_17695) prkB 3389903..3390772 (-) 870 WP_001274680.1 phosphoribulokinase -
  AM440_RS17305 (AM440_17700) yheU 3390826..3391044 (-) 219 WP_000907085.1 YheU family protein -
  AM440_RS17310 (AM440_17705) yheT 3391038..3392060 (-) 1023 WP_000057379.1 hydrolase -
  AM440_RS17315 (AM440_17710) yheS 3392060..3393973 (-) 1914 WP_063096473.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=184438 AM440_RS17285 WP_000242755.1 3388510..3389142(-) (crp) [Escherichia coli strain AR_0061]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=184438 AM440_RS17285 WP_000242755.1 3388510..3389142(-) (crp) [Escherichia coli strain AR_0061]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment