Detailed information NTG0183688

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: A9E98_RS13145
• Genome accession: NZ_CP015926
• Coordinates: 2932886..2933971 (+)
• Length: 361 a.a.
• NCBI ID: WP_015961700.1
• Uniprot ID: A0A3A6UMH7
• Organism: Legionella pneumophila strain E11_U
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2927886..2938971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A9E98_RS13120 (A9E98_13120)	-	2928279..2929028 (-)	750	WP_010948292.1	type II CAAX prenyl endopeptidase Rce1 family protein	-
A9E98_RS13125 (A9E98_13125)	rsmB	2929025..2930308 (-)	1284	WP_070065658.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
A9E98_RS13130 (A9E98_13130)	fmt	2930305..2931249 (-)	945	WP_070065659.1	methionyl-tRNA formyltransferase	-
A9E98_RS13135 (A9E98_13135)	def	2931246..2931758 (-)	513	WP_010948295.1	peptide deformylase	-
A9E98_RS13140 (A9E98_13140)	-	2931852..2932889 (+)	1038	WP_010948296.1	LysM peptidoglycan-binding domain-containing protein	-
A9E98_RS13145 (A9E98_13145)	dprA	2932886..2933971 (+)	1086	WP_015961700.1	DNA-processing protein DprA	Machinery gene
A9E98_RS13150 (A9E98_13150)	-	2933961..2934398 (+)	438	WP_015961701.1	DUF494 family protein	-
A9E98_RS13155 (A9E98_13155)	topA	2934478..2936757 (+)	2280	WP_070065660.1	type I DNA topoisomerase	-
A9E98_RS13160 (A9E98_13160)	-	2936859..2938832 (-)	1974	WP_010948300.1	acyltransferase family protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39559.72 Da
• Isoelectric Point: 7.2591

>NTDB_id=183688 A9E98_RS13145 WP_015961700.1 2932886..2933971(+) (dprA) [Legionella pneumophila strain E11_U]
MNNLQPLLALNRMKRIGPRTVLKLQKRWPDLNLMFQLSSVDLEEAGLPSWLAQTIKNFDPDFIKTDLNWLSSSENHHILT
WDSPYYPALLKEIADPPFILYAKGELSALTQPSLAIVGSRNASVTGNENARAFSREISRHGVSIVSGLALGIDAHAHLGC
LEGGGKTIAVLGTGIDCIYPRRHLKLAEQITENGLLLSEFPLKSPPIAGHFPLRNRIISGLSLCILVIEAAIKSGSLITA
RMALEQNRDVLAIPGSIHNPLARGCHYLLQQGAKLVTSVADVLDELKIEHHQFTSNKPIFSLASGKENLVKFIGFETTTI
DQIIDRSGYGMEQVTSGLAELELKGAVMAVPGGYIRCEYER

Nucleotide

• Length: 1086 bp

>NTDB_id=183688 A9E98_RS13145 WP_015961700.1 2932886..2933971(+) (dprA) [Legionella pneumophila strain E11_U]
ATGAATAATCTGCAACCCCTCCTCGCCCTAAACAGGATGAAAAGAATTGGCCCCCGAACCGTATTAAAACTGCAAAAAAG
ATGGCCTGATTTAAACCTTATGTTCCAACTGTCCAGTGTTGATCTGGAAGAAGCGGGCTTGCCATCCTGGTTGGCACAAA
CCATAAAAAATTTTGATCCGGACTTTATAAAAACTGATTTGAACTGGCTAAGTTCATCAGAAAATCATCATATTTTAACT
TGGGACTCCCCCTATTATCCCGCATTGCTCAAAGAAATAGCCGATCCTCCCTTCATTTTATACGCTAAAGGTGAGCTGTC
CGCCTTGACACAACCCAGCCTGGCTATTGTTGGAAGTCGCAATGCTTCTGTAACAGGAAACGAGAATGCCCGAGCGTTCT
CCAGGGAAATTTCCAGGCATGGGGTAAGCATAGTGAGTGGTTTAGCCTTGGGAATTGATGCTCATGCTCATTTAGGTTGT
CTGGAAGGAGGCGGCAAAACAATAGCCGTCTTAGGTACCGGAATTGATTGTATCTATCCGCGCCGGCATTTAAAATTAGC
TGAGCAAATTACAGAGAATGGTTTATTATTAAGCGAATTTCCTTTAAAAAGTCCACCAATTGCTGGACATTTTCCACTCA
GAAATCGTATAATAAGCGGTCTATCATTATGCATTTTGGTTATCGAGGCAGCAATTAAAAGCGGTTCTTTAATTACAGCA
AGAATGGCTCTGGAACAAAACAGAGATGTATTGGCCATTCCCGGATCGATTCATAACCCGTTAGCCAGGGGCTGCCACTA
CTTATTGCAGCAGGGTGCGAAATTAGTAACTTCAGTGGCTGATGTTCTTGATGAGCTAAAAATTGAGCACCATCAGTTCA
CTTCTAATAAACCAATTTTTTCCCTTGCCAGCGGTAAGGAAAACCTAGTAAAGTTCATTGGTTTTGAAACTACAACTATC
GATCAAATCATTGATCGTAGTGGATATGGCATGGAACAAGTCACGAGTGGACTGGCTGAACTAGAATTGAAAGGGGCTGT
GATGGCAGTGCCCGGTGGCTATATAAGGTGTGAATATGAAAGATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (74-277)

• DprA winged helix domain (DprA_WH) (300-353)

3D structure

• AlphaFold DB: A0A3A6UMH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	99.723	100	0.997
dprA	Vibrio cholerae strain A1552	42.895	100	0.443
dprA	Vibrio campbellii strain DS40M4	46.505	91.136	0.424
dprA	Glaesserella parasuis strain SC1401	39.418	100	0.413