Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   LLUC109_RS07635 Genome accession   NZ_CP015907
Coordinates   1510751..1511443 (-) Length   230 a.a.
NCBI ID   WP_015082645.1    Uniprot ID   A0AAJ6N309
Organism   Lactococcus cremoris strain UC109     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1505751..1516443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC109_RS07615 (LLUC109_1463) murD 1505895..1507244 (-) 1350 WP_015082642.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLUC109_RS07620 (LLUC109_1464) - 1507413..1507754 (-) 342 WP_011676628.1 P-II family nitrogen regulator -
  LLUC109_RS07625 (LLUC109_1465) - 1507839..1509080 (-) 1242 WP_015082643.1 ammonium transporter -
  LLUC109_RS07630 (LLUC109_1466) covS 1509266..1510738 (-) 1473 WP_021211938.1 HAMP domain-containing histidine kinase Regulator
  LLUC109_RS07635 (LLUC109_1467) covR 1510751..1511443 (-) 693 WP_015082645.1 response regulator transcription factor Regulator
  LLUC109_RS07640 (LLUC109_1468) - 1511599..1512129 (-) 531 WP_011834860.1 DUF177 domain-containing protein -
  LLUC109_RS07645 (LLUC109_1469) - 1512262..1512507 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLUC109_RS07650 (LLUC109_02890) - 1512831..1513193 (-) 363 Protein_1485 TIGR02328 family protein -
  LLUC109_RS07655 (LLUC109_1471) - 1513341..1513892 (+) 552 WP_021214392.1 Ltp family lipoprotein -
  LLUC109_RS07660 (LLUC109_1472) - 1514000..1514770 (+) 771 WP_015082647.1 hypothetical protein -
  LLUC109_RS07665 (LLUC109_1473) - 1514931..1516004 (-) 1074 WP_011676639.1 carbamoyl phosphate synthase small subunit -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26668.36 Da        Isoelectric Point: 5.1313

>NTDB_id=183319 LLUC109_RS07635 WP_015082645.1 1510751..1511443(-) (covR) [Lactococcus cremoris strain UC109]
MASKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEATSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMERVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=183319 LLUC109_RS07635 WP_015082645.1 1510751..1511443(-) (covR) [Lactococcus cremoris strain UC109]
ATGGCATCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCTCGTTTCGTCTCATTAGAATTAGAGCATGAAGG
CTATGCCACTGAGATTAAAGATAACGGACGTTCTGGGCTTGAAGAAGCAACTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGATGGTTTTGAAGTTGCCCGCCGTTTGCGCAAAGAAAAAGATACTCCAATTATTATGATG
ACCGCGCGTGATTCAACAATGGAACGTGTTGCCGGTCTTGATATTGGAGCAGATGATTATATTACTAAGCCTTTTGCGAT
TGAAGAACTTTTGGCTCGTGTTCGTGCATTCTTCCGTCGTGAAGAACATGGTCATGCTGTAGAACGTGCTGAAAACACTT
CTTTTCGTGATCTTGTAATTGACAAAACAAATCGTACCGTTCACCGCGGTAAAAAAGTAATTGATTTGACGCGTCGTGAA
TACGATCTTCTTTTGACGTTGATGCAAAATGTTGGGGATGTTGTCACTCGCGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACGGAAACAAATGTTGTTGATGTATATATCCGCTATCTTAGAAATAAAATTGATGTTGAAGGACAAGACA
GCTATATTCAAACCGTTCGTGGTTTGGGTTATGTGATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)

Response regulator receiver domain (Response_reg)

(6-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

99.13

100

0.991
  covR Streptococcus salivarius strain HSISS4

67.982

99.13

0.674
  vicR Streptococcus mutans UA159

45.455

100

0.457
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.43
  ciaR Streptococcus mutans UA159

37.168

98.261

0.365

Multiple sequence alignment