Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   AT729_RS12195 Genome accession   NZ_CP015886
Coordinates   2126507..2126956 (-) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   A0AA44U8B7
Organism   Neisseria meningitidis strain 38277     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 2125042..2125521 2126507..2126956 flank 986


Gene organization within MGE regions


Location: 2125042..2126956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT729_RS12175 (AT729_02053) - 2125048..2125521 (-) 474 Protein_2058 IS5/IS1182 family transposase -
  AT729_RS12185 (AT729_02054) - 2125753..2125965 (+) 213 WP_002224145.1 SWIM zinc finger domain-containing protein -
  AT729_RS14670 - 2126149..2126417 (+) 269 Protein_2060 5'-nucleotidase -
  AT729_RS12195 (AT729_02055) comP 2126507..2126956 (-) 450 WP_002214937.1 type IV pilin protein Machinery gene

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=182808 AT729_RS12195 WP_002214937.1 2126507..2126956(-) (comP) [Neisseria meningitidis strain 38277]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=182808 AT729_RS12195 WP_002214937.1 2126507..2126956(-) (comP) [Neisseria meningitidis strain 38277]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49

Multiple sequence alignment