Detailed information NTG0182741

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: B1H24_RS01175
• Genome accession: NZ_CP019978
• Coordinates: 199942..200403 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874812.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain Sag37
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 194942..205403

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B1H24_RS01140 (B1H24_01140)	-	196557..196922 (+)	366	WP_000285373.1	DUF1033 family protein	-
B1H24_RS01150 (B1H24_01150)	comGA	197095..198066 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
B1H24_RS01155 (B1H24_01155)	comGB	197960..199003 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
B1H24_RS01160 (B1H24_01160)	comGC/cglC	199000..199329 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
B1H24_RS01165 (B1H24_01165)	comGD	199304..199717 (+)	414	WP_000244261.1	competence type IV pilus minor pilin ComGD	Machinery gene
B1H24_RS01170 (B1H24_01170)	comGE	199689..199988 (+)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
B1H24_RS01175 (B1H24_01175)	comGF	199942..200403 (+)	462	WP_001874812.1	competence type IV pilus minor pilin ComGF	Machinery gene
B1H24_RS01180 (B1H24_01180)	comGG	200381..200752 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
B1H24_RS01185 (B1H24_01185)	comGH	200867..201841 (+)	975	WP_001008574.1	class I SAM-dependent methyltransferase	Machinery gene
B1H24_RS01190 (B1H24_01190)	-	201873..203066 (+)	1194	WP_000047534.1	acetate kinase	-
B1H24_RS01195 (B1H24_01195)	-	203218..203424 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
B1H24_RS01200 (B1H24_01200)	-	203483..203620 (+)	138	WP_001865900.1	hypothetical protein	-
B1H24_RS01205 (B1H24_01205)	-	203661..204116 (+)	456	WP_000905673.1	hypothetical protein	-
B1H24_RS01210 (B1H24_01210)	-	204185..204850 (+)	666	WP_000008113.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17875.89 Da
• Isoelectric Point: 9.8392

>NTDB_id=182741 B1H24_RS01175 WP_001874812.1 199942..200403(+) (comGF) [Streptococcus agalactiae strain Sag37]
MKIIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=182741 B1H24_RS01175 WP_001874812.1 199942..200403(+) (comGF) [Streptococcus agalactiae strain Sag37]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373