Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   B2J87_RS11130 Genome accession   NZ_CP019961
Coordinates   2194754..2195386 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain HKUOPY1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2189754..2200386
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B2J87_RS11105 (B2J87_11215) yhfG 2189886..2190053 (+) 168 WP_000736860.1 YhfG family protein -
  B2J87_RS11110 (B2J87_11220) fic 2190043..2190645 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  B2J87_RS11115 (B2J87_11225) pabA 2190677..2191240 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  B2J87_RS11120 (B2J87_11230) argD 2191326..2192546 (+) 1221 WP_107316971.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  B2J87_RS11125 (B2J87_11235) yhfK 2192613..2194703 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  B2J87_RS11130 (B2J87_11240) crp 2194754..2195386 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  B2J87_RS11140 (B2J87_11250) yhfA 2195688..2196092 (+) 405 WP_001148910.1 OsmC family protein -
  B2J87_RS11145 (B2J87_11255) prkB 2196147..2197016 (-) 870 WP_001274680.1 phosphoribulokinase -
  B2J87_RS11150 (B2J87_11260) yheU 2197070..2197288 (-) 219 WP_000907085.1 YheU family protein -
  B2J87_RS11155 (B2J87_11265) yheT 2197282..2198304 (-) 1023 WP_000057379.1 hydrolase -
  B2J87_RS11160 (B2J87_11270) yheS 2198304..2200217 (-) 1914 WP_089623914.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=182593 B2J87_RS11130 WP_000242755.1 2194754..2195386(-) (crp) [Escherichia coli strain HKUOPY1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=182593 B2J87_RS11130 WP_000242755.1 2194754..2195386(-) (crp) [Escherichia coli strain HKUOPY1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment