Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   B1200_RS03255 Genome accession   NZ_CP019903
Coordinates   600973..601605 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain MDR_56     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 595973..606605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B1200_RS03225 (B1200_03315) yheS 596142..598055 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  B1200_RS03230 (B1200_03320) yheT 598055..599077 (+) 1023 WP_000057375.1 hydrolase -
  B1200_RS03235 (B1200_03325) yheU 599071..599289 (+) 219 WP_000907085.1 YheU family protein -
  B1200_RS03240 (B1200_03330) prkB 599343..600212 (+) 870 WP_001274680.1 phosphoribulokinase -
  B1200_RS03245 (B1200_03335) yhfA 600267..600671 (-) 405 WP_001148908.1 OsmC family protein -
  B1200_RS03255 (B1200_03345) crp 600973..601605 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  B1200_RS03260 (B1200_03350) yhfK 601656..603746 (+) 2091 WP_001318073.1 YccS/YhfK family putative transporter -
  B1200_RS03265 (B1200_03355) argD 603813..605033 (-) 1221 WP_000963795.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  B1200_RS03270 (B1200_03360) pabA 605119..605682 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  B1200_RS03275 (B1200_03365) fic 605714..606316 (-) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  B1200_RS03280 (B1200_03370) yhfG 606306..606473 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=182127 B1200_RS03255 WP_000242755.1 600973..601605(+) (crp) [Escherichia coli strain MDR_56]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=182127 B1200_RS03255 WP_000242755.1 600973..601605(+) (crp) [Escherichia coli strain MDR_56]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467