Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   B1200_RS01475 Genome accession   NZ_CP019903
Coordinates   284759..285418 (+) Length   219 a.a.
NCBI ID   WP_078080906.1    Uniprot ID   -
Organism   Escherichia coli strain MDR_56     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 279759..290418
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B1200_RS01460 (B1200_01545) ygiS 281975..283571 (-) 1597 Protein_274 ABC transporter substrate-binding protein -
  B1200_RS01465 (B1200_01550) ygiV 283680..284162 (-) 483 WP_000183493.1 GyrI-like domain-containing protein -
  B1200_RS01470 (B1200_01555) ygiW 284215..284607 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  B1200_RS01475 (B1200_01560) ciaR 284759..285418 (+) 660 WP_078080906.1 quorum sensing response regulator transcription factor QseB Regulator
  B1200_RS01480 (B1200_01565) qseC 285415..286764 (+) 1350 WP_000673349.1 quorum sensing histidine kinase QseC -
  B1200_RS01485 (B1200_01570) mdaB 286874..287455 (+) 582 WP_000065421.1 NADPH:quinone oxidoreductase MdaB -
  B1200_RS01490 (B1200_01575) ygiN 287486..287800 (+) 315 WP_000633738.1 putative quinol monooxygenase -
  B1200_RS01495 (B1200_01580) - 287845..288732 (-) 888 WP_000614959.1 MurR/RpiR family transcriptional regulator -
  B1200_RS01500 (B1200_01585) - 288729..289676 (-) 948 WP_001318046.1 iron-siderophore ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24657.64 Da        Isoelectric Point: 7.4217

>NTDB_id=182121 B1200_RS01475 WP_078080906.1 284759..285418(+) (ciaR) [Escherichia coli strain MDR_56]
MRILLIEDDMLIGDGIKTGLSKMGFSIDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLAPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=182121 B1200_RS01475 WP_078080906.1 284759..285418(+) (ciaR) [Escherichia coli strain MDR_56]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCAT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGCCCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.426

100

0.361

Multiple sequence alignment