Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   A7327_RS08455 Genome accession   NZ_CP015646
Coordinates   1736546..1737232 (-) Length   228 a.a.
NCBI ID   WP_001788928.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 08-02300     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1731546..1742232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7327_RS08435 (A7327_08430) rpsT 1732460..1732711 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  A7327_RS08440 (A7327_08435) holA 1732756..1733730 (-) 975 WP_001282561.1 DNA polymerase III subunit delta -
  A7327_RS08445 (A7327_08440) comEC 1733787..1735988 (-) 2202 WP_049307743.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A7327_RS08450 (A7327_08445) - 1735993..1736454 (-) 462 WP_000439693.1 ComE operon protein 2 -
  A7327_RS08455 (A7327_08450) comEA 1736546..1737232 (-) 687 WP_001788928.1 ComEA family DNA-binding protein Machinery gene
  A7327_RS08460 (A7327_08455) - 1737272..1737988 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  A7327_RS08465 (A7327_08460) rsfS 1737991..1738344 (-) 354 WP_001088020.1 ribosome silencing factor -
  A7327_RS08470 (A7327_08465) yqeK 1738345..1738929 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  A7327_RS08475 (A7327_08470) nadD 1738919..1739488 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  A7327_RS08480 (A7327_08475) yhbY 1739491..1739781 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  A7327_RS08485 (A7327_08480) aroE 1739785..1740591 (-) 807 WP_000666757.1 shikimate dehydrogenase -
  A7327_RS08490 (A7327_08485) yqeH 1740605..1741705 (-) 1101 WP_001280138.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25888.59 Da        Isoelectric Point: 9.6751

>NTDB_id=181764 A7327_RS08455 WP_001788928.1 1736546..1737232(-) (comEA) [Staphylococcus aureus strain 08-02300]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=181764 A7327_RS08455 WP_001788928.1 1736546..1737232(-) (comEA) [Staphylococcus aureus strain 08-02300]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

99.561

0.996
  comEA Staphylococcus aureus MW2

97.357

99.561

0.969

Multiple sequence alignment