Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   BWR56_RS00835 Genome accession   NZ_CP019562
Coordinates   167339..169288 (+) Length   649 a.a.
NCBI ID   WP_065371519.1    Uniprot ID   -
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 162339..174288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS00810 (BWR56_0156) argR 163162..163608 (+) 447 WP_001231483.1 arginine repressor -
  BWR56_RS00815 (BWR56_0157) hexA 163659..166193 (+) 2535 WP_076984271.1 DNA mismatch repair protein MutS Machinery gene
  BWR56_RS00820 (BWR56_0158) - 166235..166693 (-) 459 WP_070695986.1 DUF3021 domain-containing protein -
  BWR56_RS00825 (BWR56_0159) - 166690..167130 (-) 441 WP_076984272.1 LytTR family DNA-binding domain-containing protein -
  BWR56_RS00835 (BWR56_0160) hexB 167339..169288 (+) 1950 WP_065371519.1 DNA mismatch repair endonuclease MutL Machinery gene
  BWR56_RS00840 (BWR56_0161) - 169429..169926 (-) 498 WP_065371520.1 helix-turn-helix domain-containing protein -
  BWR56_RS00845 (BWR56_0162) - 170099..171331 (+) 1233 WP_007520831.1 MDR family MFS transporter -
  BWR56_RS00850 (BWR56_0163) ruvA 171344..171937 (+) 594 WP_000273410.1 Holliday junction branch migration protein RuvA Machinery gene
  BWR56_RS00855 (BWR56_0164) - 171947..172510 (+) 564 WP_007520829.1 DNA-3-methyladenine glycosylase I -
  BWR56_RS00860 (BWR56_0165) - 172593..172856 (-) 264 WP_000166112.1 SemiSWEET family transporter -
  BWR56_RS00865 (BWR56_0166) - 172962..173996 (-) 1035 WP_000255130.1 S66 family peptidase -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73316.83 Da        Isoelectric Point: 5.6226

>NTDB_id=180905 BWR56_RS00835 WP_065371519.1 167339..169288(+) (hexB) [Streptococcus oralis strain S.MIT/ORALIS-351]
MSHIIELPEVLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKIQITDNGHGIAHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGQVEEVIPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLASAKKMIEIENSDLDFEITGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKERELMALVSE
AISNSLKEQALIPDALENLAKSTVRNRQKVEQTILPLKENTLYYEKTELSKPSQVEVADHQVELTEEGRDLTLFAKETLD
QLTKPAKLHFAERKPANYGQLDHPELDLASLDKAYDKLEREEASSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=180905 BWR56_RS00835 WP_065371519.1 167339..169288(+) (hexB) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGTCTCATATTATTGAATTGCCAGAAGTGTTAGCAAACCAGATCGCGGCAGGGGAGGTTATCGAACGTCCTGCCAGTGT
GGTCAAAGAGTTGGTAGAAAATGCCATTGACGCGGGTTCTAGCCAGATTATCATTGAGATTGAGGAAGCTGGTCTCAAGA
AAATTCAAATCACCGATAATGGTCATGGAATTGCCCACGATGAGGTGGAGTTGGCCTTGCGTCGCCATGCGACCAGTAAG
ATAAAAAATCAGGCAGACCTCTTTCGGATTCGGACGCTTGGTTTTCGTGGTGAAGCCCTGCCTTCTATCGCTTCTGTCAG
TGTGCTGACTCTGTTGACGGCGGTGGATGGTGCGAGTCATGGGACTAAGTTAGTCGCGCGTGGAGGTCAAGTTGAGGAAG
TCATCCCAGCGACTAGCCCTGTAGGAACCAAAGTTTGTGTGGAAGACCTCTTTTTCAACACACCTGCCCGTCTCAAGTAT
ATGAAGAGCCAGCAAGCGGAGCTGTCTCATATCATTGATATTGTCAACCGTCTGGGATTAGCTCATCCTGAGATTTCCTT
CAGTTTGATTAGTGATGGCAAGGAAATGACGCGGACAGCAGGGACTGGTCAACTGCGTCAAGCCATCGCAGGGATTTATG
GTTTGGCGAGTGCTAAGAAGATGATTGAAATTGAGAACTCTGACTTAGATTTTGAAATTACAGGTTTTGTGTCTCTGCCT
GAGTTAACTCGAGCAAATCGTAACTATATCAGCCTCTTCATCAATGGCCGCTATATCAAGAACTTCTTGCTCAATCGCGC
TATTCTTGATGGTTATGGAAGCAAACTCATGGTAGGGCGTTTTCCACTGGCTGTCATTCACATCCATATTGACCCCTATC
TAGCTGATGTCAATGTCCATCCAACTAAGCAAGAAGTGCGGATTTCTAAGGAAAGAGAACTGATGGCGCTGGTTTCAGAA
GCTATTTCAAATAGTCTCAAGGAACAAGCCTTGATTCCTGATGCTTTAGAAAATCTTGCCAAGTCGACCGTGCGCAATCG
TCAAAAGGTAGAGCAGACCATTCTCCCACTCAAAGAAAATACGCTCTACTATGAAAAAACAGAACTCTCAAAACCTAGTC
AAGTTGAGGTGGCTGATCACCAGGTTGAATTAACTGAGGAGGGTAGGGACCTAACTCTGTTTGCCAAGGAAACCTTGGAC
CAGCTAACCAAGCCCGCAAAACTGCATTTTGCAGAGAGAAAGCCTGCTAACTATGGCCAATTAGACCATCCAGAGTTAGA
TCTTGCTAGCCTCGATAAGGCTTATGATAAGCTGGAGCGAGAAGAAGCATCGAGTTTCCCAGAGTTGGAGTTCTTCGGAC
AGATGCACGGGACTTATCTTTTTGCCCAAGGGCGAGATGGACTCTACATCATAGACCAGCACGCGGCTCAGGAACGAGTC
AAGTACGAGGAATACCGTGAAAGCATCGGCAATGTTGACCAGAGCCAGCAGCAACTCCTAGTGCCCTACATCTTTGAATT
TCCTGCGGATGATGCGCTTCGTCTCAAGGAAAGAATGCCTCTTTTAGAGGAAGTGGGTGTCTTTCTAGCAGAGTACGGAG
AAAATCAATTTATCCTGCGTGAACATCCTATTTGGATGGCAGAAGAGGAGATTGAGTCAGGCATCTATGAAATGTGTGAT
ATGCTCCTTTTGACCAAGGAAGTTTCGATCAAGAAATACCGAGCAGAGCTGGCTATCATGATGTCCTGCAAACGGTCTAT
CAAGGCCAACCATCGCATCGATGACCACTCAGCCAGACAACTCCTTTATCAGCTTTCTCAATGTGACAATCCTTACAACT
GTCCCCACGGACGTCCTGTTTTGGTGCATTTTACCAAGTCGGATATGGAAAAAATGTTCCGACGAATTCAGGAGAATCAT
ACTAGCCTCCGTGAGTTGGGGAAATATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-107)

MutL C terminal dimerisation domain (MutL_C)

(450-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

96.918

100

0.969