Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   A6M16_RS02200 Genome accession   NZ_CP015557
Coordinates   421218..422510 (+) Length   430 a.a.
NCBI ID   WP_024395771.1    Uniprot ID   -
Organism   Streptococcus suis strain DN13     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 416218..427510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M16_RS02175 (A6M16_02175) - 417023..417664 (+) 642 WP_002937025.1 response regulator transcription factor -
  A6M16_RS02180 (A6M16_02180) - 417714..419114 (+) 1401 WP_014637530.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  A6M16_RS02185 (A6M16_02185) - 419116..419487 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  A6M16_RS02190 (A6M16_02190) cysK 419513..420439 (-) 927 WP_015646509.1 cysteine synthase A -
  A6M16_RS02195 (A6M16_02195) - 420529..421161 (-) 633 WP_024389592.1 YigZ family protein -
  A6M16_RS02200 (A6M16_02200) comFA/cflA 421218..422510 (+) 1293 WP_024395771.1 DEAD/DEAH box helicase Machinery gene
  A6M16_RS02205 (A6M16_02205) - 422503..423168 (+) 666 WP_024389594.1 ComF family protein -
  A6M16_RS02210 (A6M16_02210) hpf 423245..423787 (+) 543 WP_004194117.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48867.38 Da        Isoelectric Point: 9.0447

>NTDB_id=180673 A6M16_RS02200 WP_024395771.1 421218..422510(+) (comFA/cflA) [Streptococcus suis strain DN13]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQNDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLFTASSLVQIAGRVGRSIERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=180673 A6M16_RS02200 WP_024395771.1 421218..422510(+) (comFA/cflA) [Streptococcus suis strain DN13]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACGACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAATGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAATTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATTTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAATTA
GATAAAAAAGTCAGAACAGGTAAATTAAGCCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTCCCCTTACTCATTTTTGTCCCAGAAATCTCTAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTTCACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGGGTCGGCAGGAGTATAGAACGTCCGACTGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.285

100

0.674
  comFA/cflA Streptococcus pneumoniae Rx1

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae D39

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae R6

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae TIGR4

66.589

100

0.667
  comFA/cflA Streptococcus mitis SK321

66.125

100

0.663
  comFA Lactococcus lactis subsp. cremoris KW2

54.408

92.326

0.502
  comFA Latilactobacillus sakei subsp. sakei 23K

38.106

100

0.384
  comFA Bacillus subtilis subsp. subtilis str. 168

37.831

96.512

0.365

Multiple sequence alignment