Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A2I66_RS05325 Genome accession   NZ_CP015535
Coordinates   1116351..1116980 (+) Length   209 a.a.
NCBI ID   WP_065865303.1    Uniprot ID   -
Organism   Staphylococcus carnosus strain TMW 2.218     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1111351..1121980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2I66_RS05300 (A2I66_05210) - 1112070..1113056 (-) 987 WP_253720581.1 aromatic acid exporter family protein -
  A2I66_RS05305 (A2I66_05215) map 1113308..1114075 (+) 768 WP_065865301.1 type I methionyl aminopeptidase -
  A2I66_RS05310 (A2I66_05220) - 1114209..1114604 (+) 396 WP_015900706.1 hypothetical protein -
  A2I66_RS05315 (A2I66_05225) liaF 1114620..1115321 (+) 702 WP_253720582.1 cell wall-active antibiotics response protein LiaF -
  A2I66_RS05320 (A2I66_05230) vraS 1115318..1116361 (+) 1044 WP_065865302.1 sensor histidine kinase Regulator
  A2I66_RS05325 (A2I66_05235) vraR 1116351..1116980 (+) 630 WP_065865303.1 response regulator transcription factor Regulator
  A2I66_RS05330 (A2I66_05240) - 1117030..1117608 (-) 579 WP_015900702.1 carbonic anhydrase -
  A2I66_RS05335 (A2I66_05245) - 1117818..1118894 (-) 1077 WP_065865304.1 YihY/virulence factor BrkB family protein -
  A2I66_RS05340 (A2I66_05250) - 1119013..1119309 (-) 297 WP_015900700.1 hypothetical protein -
  A2I66_RS05345 (A2I66_05255) - 1119317..1119781 (-) 465 WP_046100414.1 low molecular weight protein-tyrosine-phosphatase -
  A2I66_RS05350 (A2I66_05260) - 1120017..1120223 (+) 207 WP_015900698.1 DUF1128 family protein -
  A2I66_RS05355 (A2I66_05265) - 1120262..1121500 (+) 1239 WP_015900697.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23721.21 Da        Isoelectric Point: 4.7025

>NTDB_id=180499 A2I66_RS05325 WP_065865303.1 1116351..1116980(+) (vraR) [Staphylococcus carnosus strain TMW 2.218]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELHPDLILMDLLMEDMDGVEATQQIKKDLPNIKVL
MLTSYIEDNEVYRALDAGVDSYILKTTSASDIAEAIRKTQHNESVFEAEVLVKMRNRMNQRAELYEMLTDREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHDLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=180499 A2I66_RS05325 WP_065865303.1 1116351..1116980(+) (vraR) [Staphylococcus carnosus strain TMW 2.218]
ATGACGATTAAAGTGCTATTTGTTGATGACCATGAAATGGTGCGTATCGGCATTTCAAGTTATTTATCAACACAACCAGA
TATTGAAGTAGTAGGGGAAGGTAAATCTGGTAAAGAAGCTATTGAAAAAGCACATGAACTACATCCTGATTTAATTTTGA
TGGATTTATTGATGGAGGATATGGATGGTGTTGAAGCAACACAGCAAATCAAAAAAGATTTACCGAATATTAAAGTGTTG
ATGTTAACAAGTTACATTGAAGATAACGAAGTATATCGTGCATTAGATGCAGGGGTAGACAGTTATATCCTTAAAACAAC
CAGTGCAAGCGACATTGCAGAGGCAATCAGAAAAACACAACATAATGAATCTGTATTTGAAGCGGAAGTACTCGTTAAAA
TGCGTAATCGCATGAATCAACGTGCGGAATTATATGAAATGCTAACAGATAGAGAAATGGAAATTCTTTTATTAATTGCA
AAAGGATATTCTAACCAAGAAATTGCAAGTGCATCACACATAACTATTAAAACAGTAAAAACGCATGTAAGTAATATATT
AAGTAAATTAGAAGTACAAGATAGAACACAAGCTGTGATATATGCATTCCAACATGATTTGATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.909

100

0.909
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment