Detailed information NTG0180498

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: A2I66_RS05320
• Genome accession: NZ_CP015535
• Coordinates: 1115318..1116361 (+)
• Length: 347 a.a.
• NCBI ID: WP_065865302.1
• Uniprot ID: -
• Organism: Staphylococcus carnosus strain TMW 2.218
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1110318..1121361

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2I66_RS05295 (A2I66_05205)	-	1111295..1112020 (+)	726	WP_015900709.1	type 1 glutamine amidotransferase	-
A2I66_RS05300 (A2I66_05210)	-	1112070..1113056 (-)	987	WP_253720581.1	aromatic acid exporter family protein	-
A2I66_RS05305 (A2I66_05215)	map	1113308..1114075 (+)	768	WP_065865301.1	type I methionyl aminopeptidase	-
A2I66_RS05310 (A2I66_05220)	-	1114209..1114604 (+)	396	WP_015900706.1	hypothetical protein	-
A2I66_RS05315 (A2I66_05225)	liaF	1114620..1115321 (+)	702	WP_253720582.1	cell wall-active antibiotics response protein LiaF	-
A2I66_RS05320 (A2I66_05230)	vraS	1115318..1116361 (+)	1044	WP_065865302.1	sensor histidine kinase	Regulator
A2I66_RS05325 (A2I66_05235)	vraR	1116351..1116980 (+)	630	WP_065865303.1	response regulator transcription factor	Regulator
A2I66_RS05330 (A2I66_05240)	-	1117030..1117608 (-)	579	WP_015900702.1	carbonic anhydrase	-
A2I66_RS05335 (A2I66_05245)	-	1117818..1118894 (-)	1077	WP_065865304.1	YihY/virulence factor BrkB family protein	-
A2I66_RS05340 (A2I66_05250)	-	1119013..1119309 (-)	297	WP_015900700.1	hypothetical protein	-
A2I66_RS05345 (A2I66_05255)	-	1119317..1119781 (-)	465	WP_046100414.1	low molecular weight protein-tyrosine-phosphatase	-
A2I66_RS05350 (A2I66_05260)	-	1120017..1120223 (+)	207	WP_015900698.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40135.63 Da
• Isoelectric Point: 5.4382

>NTDB_id=180498 A2I66_RS05320 WP_065865302.1 1115318..1116361(+) (vraS) [Staphylococcus carnosus strain TMW 2.218]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQHIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMIQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFKVPKGIEDHLFRITQEGISNTLRHAEGSKLTIDLYNKDDYLLLRIQDDGKGFDIDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=180498 A2I66_RS05320 WP_065865302.1 1115318..1116361(+) (vraS) [Staphylococcus carnosus strain TMW 2.218]
ATGAACCATTATATAAGAGCTATAGGTTCAATGTTAATACTGATTTACAGTATTTTAGCCATATTCTTTTTCATTGATAA
AGTCTTTGTAAATATTATCTTTTTTCAAGGAATGTTCTATACACAAATTTTTGGGATTCCGGTATTTTTGTTTTTAAATA
TCATTGTGATACTTATGTCTATTATCGTAGGTTCTGTTTTAGCATATAAGGTCAACCAGCAAAACCACTGGATTAAAGAT
CAAATTGAACATTCAATTGAAGGTGAAGTAGTTGGAATAAATGATCAACATATCGAACTTTATCAAGAAACACTCGATAT
TTACCATATGCTAGTACCTTTAAACCAAGAATTACATCGCTTACGTATCAAGACACAAGATTTAACGAATGAAACTTATA
ATTTGAATGATACAAAAGTGAAGAAAATTATAGAAGATGAACGTCAGCGTTTGGCCAGAGAATTGCATGACTCAGTCAGT
CAGCAATTATTTGCTGCGAGTATGATGTTATCTGCTATTAAAGAAACGAAGTTAGAACCGCCTTTAGATCAGCAAATTCC
AACACTTGAAAAAATGATTCAAGATTCACAACTTGAAATGCGTGCTTTATTACTCCATTTGCGTCCGTTAGGCTTGAAGG
ATCGCTCATTAGGAGAAGGTATTAAAGACTTGGTTGTGGACTTGCAGAAAAAAGTGCCGATGAAAGTAGTATATGACATC
GAAGATTTTAAAGTACCAAAAGGGATTGAAGATCATTTATTTCGTATTACCCAAGAAGGTATTTCAAATACGCTAAGACA
TGCTGAAGGTTCAAAATTAACAATAGATTTATATAATAAAGACGATTACTTACTTTTACGTATTCAAGATGATGGTAAAG
GTTTTGATATAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	84.726	100	0.847