Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A6045_RS08475 Genome accession   NZ_CP015433
Coordinates   1724721..1725398 (-) Length   225 a.a.
NCBI ID   WP_192940796.1    Uniprot ID   -
Organism   [Haemophilus] ducreyi strain GHA8     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1719721..1730398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6045_RS08455 (A6045_08480) mutL 1720083..1721879 (+) 1797 WP_010944705.1 DNA mismatch repair endonuclease MutL -
  A6045_RS08460 (A6045_08485) miaA 1721943..1722884 (+) 942 WP_010944704.1 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA -
  A6045_RS08465 (A6045_08490) hfq 1722959..1723264 (+) 306 WP_010944703.1 RNA chaperone Hfq -
  A6045_RS08470 (A6045_08495) hflX 1723302..1724651 (+) 1350 WP_010944702.1 ribosome rescue GTPase HflX -
  A6045_RS08475 (A6045_08500) crp 1724721..1725398 (-) 678 WP_192940796.1 cAMP-activated global transcriptional regulator CRP Regulator
  A6045_RS08480 (A6045_08505) - 1725489..1725707 (-) 219 WP_010944700.1 YheU family protein -
  A6045_RS08485 (A6045_08510) slmA 1725716..1726324 (-) 609 WP_010944699.1 nucleoid occlusion factor SlmA -
  A6045_RS08490 (A6045_08515) dut 1726428..1726883 (-) 456 WP_041603414.1 dUTP diphosphatase -
  A6045_RS08495 (A6045_08520) coaBC 1726870..1728114 (-) 1245 WP_010944697.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  A6045_RS08500 (A6045_08525) radC 1728328..1728999 (+) 672 WP_010944696.1 RadC family protein -
  A6045_RS08505 (A6045_08530) rpmB 1729160..1729396 (+) 237 WP_010944695.1 50S ribosomal protein L28 -
  A6045_RS08510 (A6045_08535) rpmG 1729408..1729578 (+) 171 WP_010944694.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25243.13 Da        Isoelectric Point: 6.5815

>NTDB_id=179637 A6045_RS08475 WP_192940796.1 1724721..1725398(-) (crp) [[Haemophilus] ducreyi strain GHA8]
MQDISISTPRLDGEVSPPPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEEANSLFYIVSGSVAVFIKDDEGKEMILSHLG
QGEFVGEISLFEENTQPRTAWVKTKDACEIAEISYKKFKQLVHVNPDILMYLAAQMACRLRQTSRQVSNLAFLDVTGRIA
QTLMNLAKMPEAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide


Download         Length: 678 bp        

>NTDB_id=179637 A6045_RS08475 WP_192940796.1 1724721..1725398(-) (crp) [[Haemophilus] ducreyi strain GHA8]
ATGCAAGATATTTCTATTTCTACACCTCGACTTGATGGAGAGGTTTCCCCGCCTCCTTCGATTCATGATCCTGCGGTAGA
ATGGTTTTTAACGCACTGCCATATTCATCGCTATCCTTCAAAATATACTTTAATTCACGCAGGTGAAGAAGCAAATTCCC
TGTTTTATATTGTCAGTGGTTCTGTGGCTGTCTTTATTAAAGACGATGAAGGCAAAGAAATGATTTTATCACATCTAGGA
CAAGGAGAGTTTGTCGGCGAAATTAGTTTATTTGAAGAAAACACACAGCCAAGAACCGCTTGGGTAAAAACGAAAGATGC
TTGCGAAATTGCAGAAATTTCTTATAAAAAATTTAAACAATTAGTACATGTAAATCCTGACATTTTAATGTATCTTGCTG
CTCAAATGGCTTGTCGCTTACGTCAAACTTCGCGTCAAGTAAGTAATCTTGCTTTTTTAGATGTTACCGGTCGTATTGCG
CAAACATTGATGAATTTAGCCAAAATGCCTGAAGCAATGACGCATCCTGAAGGAATGCAAATTAAAATTACTCGCCAAGA
AATTGGGCAAATGGTGGGCTGCTCACGTGAAACTGTGGGACGCATTTTAAAAATGTTAGAAGATGAAGGTTTAATCTCAG
CCCATGGGAAGACCATAGTTGTTTATGGTACGCGTTAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(37-123)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(157-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

75.862

90.222

0.684
  crp Haemophilus influenzae Rd KW20

73.892

90.222

0.667
  crp Acinetobacter baumannii D1279779

49.5

88.889

0.44

Multiple sequence alignment