Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A6042_RS06125 Genome accession   NZ_CP015430
Coordinates   1291776..1292453 (+) Length   225 a.a.
NCBI ID   WP_172592915.1    Uniprot ID   -
Organism   [Haemophilus] ducreyi strain GHA2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1286776..1297453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6042_RS06090 (A6042_06090) rpmG 1287598..1287768 (-) 171 WP_010944694.1 50S ribosomal protein L33 -
  A6042_RS06095 (A6042_06095) rpmB 1287780..1288016 (-) 237 WP_005599762.1 50S ribosomal protein L28 -
  A6042_RS06100 (A6042_06100) radC 1288177..1288848 (-) 672 WP_064083359.1 RadC family protein -
  A6042_RS06105 (A6042_06105) coaBC 1289061..1290305 (+) 1245 WP_064082181.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  A6042_RS06110 (A6042_06110) dut 1290292..1290747 (+) 456 WP_041603414.1 dUTP diphosphatase -
  A6042_RS06115 (A6042_06115) slmA 1290851..1291458 (+) 608 Protein_1182 nucleoid occlusion factor SlmA -
  A6042_RS06120 (A6042_06120) - 1291467..1291685 (+) 219 WP_010944700.1 YheU family protein -
  A6042_RS06125 (A6042_06125) crp 1291776..1292453 (+) 678 WP_172592915.1 cAMP-activated global transcriptional regulator CRP Regulator
  A6042_RS06130 (A6042_06130) hflX 1292523..1293872 (-) 1350 WP_064082178.1 ribosome rescue GTPase HflX -
  A6042_RS06135 (A6042_06135) hfq 1293910..1294215 (-) 306 WP_064082177.1 RNA chaperone Hfq -
  A6042_RS06140 (A6042_06140) miaA 1294278..1295219 (-) 942 WP_064082176.1 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA -
  A6042_RS06145 (A6042_06145) mutL 1295283..1297079 (-) 1797 WP_064082175.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25244.07 Da        Isoelectric Point: 6.2235

>NTDB_id=179562 A6042_RS06125 WP_172592915.1 1291776..1292453(+) (crp) [[Haemophilus] ducreyi strain GHA2]
MQDISISTPRLDGEVSPPPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEEANSLFYIVSGSVAVFIKDDEGKEMILSHLG
QGEFVGEISLFEENTQPRTAWVKTKDACEIAEISYEKFKQLVHVNPDILMYLAAQMACRLRQTSRQVSNLAFLDVTGRIA
QTLMNLAKMPEAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide


Download         Length: 678 bp        

>NTDB_id=179562 A6042_RS06125 WP_172592915.1 1291776..1292453(+) (crp) [[Haemophilus] ducreyi strain GHA2]
ATGCAAGATATTTCTATTTCTACACCTCGGCTTGATGGAGAGGTTTCCCCGCCTCCTTCGATTCATGATCCTGCGGTAGA
ATGGTTTTTAACGCACTGCCATATTCATCGCTATCCTTCAAAATATACTTTAATTCACGCAGGTGAAGAAGCAAATTCCC
TGTTTTATATTGTCAGTGGTTCTGTGGCTGTCTTTATTAAAGACGATGAAGGCAAAGAAATGATTTTATCACATCTAGGA
CAAGGAGAGTTTGTCGGCGAAATTAGTTTATTTGAAGAAAATACACAGCCAAGAACCGCTTGGGTAAAAACGAAAGATGC
TTGCGAAATTGCAGAAATTTCTTATGAAAAATTTAAACAATTAGTACATGTAAATCCTGACATTTTAATGTATCTTGCTG
CTCAAATGGCTTGTCGCTTACGTCAAACTTCGCGTCAAGTAAGTAATCTTGCTTTTTTAGATGTTACCGGTCGTATTGCG
CAAACATTGATGAATTTAGCCAAAATGCCTGAAGCAATGACGCATCCTGAAGGAATGCAAATTAAAATTACTCGCCAAGA
AATTGGGCAAATGGTGGGCTGCTCACGTGAAACTGTGGGACGCATTTTAAAAATGTTAGAAGATGAAGGTTTAATCTCAG
CCCATGGGAAGACCATAGTTGTTTATGGTACGCGTTAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(37-123)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(157-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

75.369

90.222

0.68
  crp Haemophilus influenzae Rd KW20

73.399

90.222

0.662
  crp Acinetobacter baumannii D1279779

49.5

88.889

0.44

Multiple sequence alignment