Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BWI88_RS11255 Genome accession   NZ_CP019271
Coordinates   2248618..2249250 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 13P460A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2243618..2254250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWI88_RS11230 (BWI88_11220) yhfG 2243750..2243917 (+) 168 WP_000736862.1 YhfG family protein -
  BWI88_RS11235 (BWI88_11225) fic 2243907..2244509 (+) 603 WP_148125457.1 putative adenosine monophosphate-protein transferase Fic -
  BWI88_RS11240 (BWI88_11230) pabA 2244541..2245104 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  BWI88_RS11245 (BWI88_11235) argD 2245190..2246410 (+) 1221 WP_000963784.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BWI88_RS11250 (BWI88_11240) yhfK 2246477..2248567 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  BWI88_RS11255 (BWI88_11245) crp 2248618..2249250 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BWI88_RS11265 (BWI88_11255) yhfA 2249552..2249956 (+) 405 WP_001148908.1 OsmC family protein -
  BWI88_RS11270 (BWI88_11260) prkB 2250011..2250880 (-) 870 WP_001274680.1 phosphoribulokinase -
  BWI88_RS11275 (BWI88_11265) yheU 2250934..2251152 (-) 219 WP_000907085.1 YheU family protein -
  BWI88_RS11280 (BWI88_11270) yheT 2251146..2252168 (-) 1023 WP_000057405.1 hydrolase -
  BWI88_RS11285 (BWI88_11275) yheS 2252168..2254081 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=179515 BWI88_RS11255 WP_000242755.1 2248618..2249250(-) (crp) [Escherichia coli strain 13P460A]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=179515 BWI88_RS11255 WP_000242755.1 2248618..2249250(-) (crp) [Escherichia coli strain 13P460A]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAAGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment