Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BWI82_RS13425 Genome accession   NZ_CP019243
Coordinates   2581027..2581659 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain Combat2C1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2576027..2586659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWI82_RS13395 (BWI82_13400) yheS 2576196..2578109 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  BWI82_RS13400 (BWI82_13405) yheT 2578109..2579131 (+) 1023 WP_000057389.1 hydrolase -
  BWI82_RS13405 (BWI82_13410) yheU 2579125..2579343 (+) 219 WP_000907085.1 YheU family protein -
  BWI82_RS13410 (BWI82_13415) prkB 2579397..2580266 (+) 870 WP_001274680.1 phosphoribulokinase -
  BWI82_RS13415 (BWI82_13420) yhfA 2580321..2580725 (-) 405 WP_001148908.1 OsmC family protein -
  BWI82_RS13425 (BWI82_13430) crp 2581027..2581659 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BWI82_RS13430 (BWI82_13435) yhfK 2581710..2583800 (+) 2091 WP_001298205.1 YccS/YhfK family putative transporter -
  BWI82_RS13435 (BWI82_13440) argD 2583878..2585098 (-) 1221 WP_000963809.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BWI82_RS13440 (BWI82_13445) pabA 2585184..2585747 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  BWI82_RS13445 (BWI82_13450) fic 2585779..2586381 (-) 603 WP_001280615.1 putative adenosine monophosphate-protein transferase Fic -
  BWI82_RS13450 (BWI82_13455) yhfG 2586371..2586538 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=179027 BWI82_RS13425 WP_000242755.1 2581027..2581659(+) (crp) [Escherichia coli strain Combat2C1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=179027 BWI82_RS13425 WP_000242755.1 2581027..2581659(+) (crp) [Escherichia coli strain Combat2C1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467