Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BE963_RS07405 Genome accession   NZ_CP018957
Coordinates   877160..877792 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain Ecol_316     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 872160..882792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BE963_RS07375 (BE963_07590) yheS 872329..874242 (+) 1914 WP_000634839.1 ABC transporter ATP-binding protein -
  BE963_RS07380 (BE963_07595) yheT 874242..875264 (+) 1023 WP_001586325.1 hydrolase -
  BE963_RS07385 (BE963_07600) yheU 875258..875476 (+) 219 WP_000907085.1 YheU family protein -
  BE963_RS07390 (BE963_07605) prkB 875530..876399 (+) 870 WP_001274684.1 phosphoribulokinase -
  BE963_RS07395 (BE963_07610) yhfA 876454..876858 (-) 405 WP_001148908.1 OsmC family protein -
  BE963_RS07405 (BE963_07620) crp 877160..877792 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BE963_RS07410 (BE963_07625) yhfK 877843..879933 (+) 2091 WP_001306309.1 YccS/YhfK family putative transporter -
  BE963_RS07415 (BE963_07630) argD 880000..881220 (-) 1221 WP_000963771.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BE963_RS07420 (BE963_07635) pabA 881306..881869 (-) 564 WP_000601857.1 aminodeoxychorismate synthase component 2 -
  BE963_RS07425 (BE963_07640) fic 881901..882503 (-) 603 WP_001586327.1 putative adenosine monophosphate-protein transferase Fic -
  BE963_RS07430 (BE963_07645) yhfG 882493..882660 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=177102 BE963_RS07405 WP_000242755.1 877160..877792(+) (crp) [Escherichia coli strain Ecol_316]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=177102 BE963_RS07405 WP_000242755.1 877160..877792(+) (crp) [Escherichia coli strain Ecol_316]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGATGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467