Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BUQ71_RS06235 Genome accession   NZ_CP018840
Coordinates   1189721..1190353 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain KSC64     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1184721..1195353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUQ71_RS06205 (BUQ71_06320) yheS 1184890..1186803 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  BUQ71_RS06210 (BUQ71_06325) yheT 1186803..1187825 (+) 1023 WP_000057405.1 hydrolase -
  BUQ71_RS06215 (BUQ71_06330) yheU 1187819..1188037 (+) 219 WP_000907085.1 YheU family protein -
  BUQ71_RS06220 (BUQ71_06335) prkB 1188091..1188960 (+) 870 WP_001274680.1 phosphoribulokinase -
  BUQ71_RS06225 (BUQ71_06340) yhfA 1189015..1189419 (-) 405 WP_001148908.1 OsmC family protein -
  BUQ71_RS06235 (BUQ71_06350) crp 1189721..1190353 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BUQ71_RS06240 (BUQ71_06355) yhfK 1190404..1192494 (+) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  BUQ71_RS06245 (BUQ71_06360) argD 1192561..1193781 (-) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BUQ71_RS06250 (BUQ71_06365) pabA 1193867..1194430 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  BUQ71_RS06255 (BUQ71_06370) fic 1194462..1195064 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  BUQ71_RS06260 (BUQ71_06375) yhfG 1195054..1195221 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=176437 BUQ71_RS06235 WP_000242755.1 1189721..1190353(+) (crp) [Escherichia coli strain KSC64]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=176437 BUQ71_RS06235 WP_000242755.1 1189721..1190353(+) (crp) [Escherichia coli strain KSC64]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467