Detailed information NTG0176365

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: BUM80_RS07345
• Genome accession: NZ_CP018838
• Coordinates: 1350804..1351703 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904833.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 11A
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1345804..1356703

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUM80_RS07320 (BUM80_07520)	rsmA	1346134..1347006 (-)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
BUM80_RS07325 (BUM80_07525)	-	1347137..1347445 (-)	309	WP_000333257.1	hypothetical protein	-
BUM80_RS07330 (BUM80_07530)	-	1347438..1348079 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
BUM80_RS07335 (BUM80_07535)	-	1348081..1350111 (-)	2031	WP_000825257.1	bacteriocin-associated integral membrane family protein	-
BUM80_RS07340 (BUM80_07540)	-	1350188..1350484 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
BUM80_RS07345 (BUM80_07545)	comR	1350804..1351703 (-)	900	WP_000904833.1	helix-turn-helix transcriptional regulator	Regulator
BUM80_RS07350 (BUM80_07550)	rnmV	1351775..1352335 (-)	561	WP_000664448.1	ribonuclease M5	-
BUM80_RS07355 (BUM80_07555)	-	1352335..1353108 (-)	774	WP_000575638.1	TatD family hydrolase	-
BUM80_RS07365 (BUM80_07565)	-	1353413..1354384 (-)	972	Protein_1371	DUF1542 domain-containing protein	-
BUM80_RS07375 (BUM80_07570)	rpmH	1354590..1354724 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
BUM80_RS07380 (BUM80_07575)	-	1354869..1356083 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
BUM80_RS07385 (BUM80_07580)	-	1356239..1356533 (-)	295	Protein_1374	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35335.16 Da
• Isoelectric Point: 4.8989

>NTDB_id=176365 BUM80_RS07345 WP_000904833.1 1350804..1351703(-) (comR) [Streptococcus pneumoniae strain 11A]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=176365 BUM80_RS07345 WP_000904833.1 1350804..1351703(-) (comR) [Streptococcus pneumoniae strain 11A]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	38.144	97.324	0.371
comR	Streptococcus suis 05ZYH33	38.144	97.324	0.371
comR	Streptococcus suis D9	36.12	100	0.361