Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   BUM80_RS03310 Genome accession   NZ_CP018838
Coordinates   638149..639498 (-) Length   449 a.a.
NCBI ID   WP_100910888.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 11A     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 633149..644498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUM80_RS03280 (BUM80_03385) - 633262..634248 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  BUM80_RS03285 (BUM80_03390) - 634537..635280 (-) 744 Protein_620 potassium channel family protein -
  BUM80_RS03290 (BUM80_03395) - 635327..635581 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  BUM80_RS03295 (BUM80_03400) relB 635583..635825 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  BUM80_RS03300 (BUM80_03405) - 636019..637275 (+) 1257 WP_000530078.1 ISL3 family transposase -
  BUM80_RS03305 (BUM80_03410) vicX 637338..638147 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  BUM80_RS03310 (BUM80_03415) micB 638149..639498 (-) 1350 WP_100910888.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BUM80_RS03315 (BUM80_03420) yycF 639491..640195 (-) 705 WP_000722076.1 response regulator YycF -
  BUM80_RS03320 (BUM80_03425) mutY 640251..641426 (-) 1176 WP_000886152.1 A/G-specific adenine glycosylase -
  BUM80_RS12000 (BUM80_03430) - 641523..641648 (+) 126 WP_001818232.1 hypothetical protein -
  BUM80_RS03325 (BUM80_03435) - 641754..643424 (-) 1671 WP_000845285.1 formate--tetrahydrofolate ligase -
  BUM80_RS03330 (BUM80_03440) coaB 643654..644343 (+) 690 WP_000699494.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51764.49 Da        Isoelectric Point: 4.8612

>NTDB_id=176328 BUM80_RS03310 WP_100910888.1 638149..639498(-) (micB) [Streptococcus pneumoniae strain 11A]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGESEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVATDFIKVSLDETNRMMRMVTDLLHLSRIDNATSLLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=176328 BUM80_RS03310 WP_100910888.1 638149..639498(-) (micB) [Streptococcus pneumoniae strain 11A]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGAGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACCAACCGTCGGGGTCAGATTATCATGATTAATGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGAGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCAACAGACTTTATCAAGGTTTCTCTTGATGAGACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCTCCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(98-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.109

100

0.991
  vicK Streptococcus mutans UA159

69.403

89.532

0.621