Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   BUM80_RS02235 Genome accession   NZ_CP018838
Coordinates   420988..421638 (+) Length   216 a.a.
NCBI ID   WP_000387329.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 11A     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 415988..426638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUM80_RS02200 (BUM80_02285) - 416511..417011 (+) 501 WP_000566988.1 GNAT family N-acetyltransferase -
  BUM80_RS02205 (BUM80_02290) - 417014..417340 (+) 327 Protein_416 TfoX/Sxy family protein -
  BUM80_RS11675 ald 417641..418728 (-) 1088 Protein_417 alanine dehydrogenase -
  BUM80_RS02225 (BUM80_02310) - 418762..420018 (-) 1257 WP_000530081.1 ISL3 family transposase -
  BUM80_RS02230 (BUM80_02315) - 420351..420920 (+) 570 WP_000443772.1 GNAT family N-acetyltransferase -
  BUM80_RS02235 (BUM80_02320) comEA/celA/cilE 420988..421638 (+) 651 WP_000387329.1 helix-hairpin-helix domain-containing protein Machinery gene
  BUM80_RS02240 (BUM80_02325) comEC/celB 421622..423862 (+) 2241 WP_000942408.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  BUM80_RS02245 (BUM80_02330) - 424041..424229 (+) 189 WP_001810030.1 hypothetical protein -
  BUM80_RS02250 (BUM80_02335) - 424262..424849 (+) 588 WP_000939886.1 ATP-binding cassette domain-containing protein -
  BUM80_RS02255 (BUM80_02340) - 424853..426037 (+) 1185 WP_000655949.1 ABC transporter permease -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23254.66 Da        Isoelectric Point: 5.9204

>NTDB_id=176313 BUM80_RS02235 WP_000387329.1 420988..421638(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 11A]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVHKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEESVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=176313 BUM80_RS02235 WP_000387329.1 420988..421638(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 11A]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCATAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAATCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae D39

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae R6

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

96.296

100

0.963
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.37

100

0.954
  comEA/celA/cilE Streptococcus mitis SK321

90.278

100

0.903
  comEA Lactococcus lactis subsp. cremoris KW2

43.612

100

0.458
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361

Multiple sequence alignment