Detailed information NTG0176083

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: BTV22_RS08880
• Genome accession: NZ_CP018807
• Coordinates: 1971772..1972416 (+)
• Length: 214 a.a.
• NCBI ID: WP_011608291.1
• Uniprot ID: -
• Organism: Histophilus somni strain USDA-ARS-USMARC-63373
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1966772..1977416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BTV22_RS08845 (BTV22_08815)	rpmG	1967683..1967853 (-)	171	WP_005542835.1	50S ribosomal protein L33	-
BTV22_RS08850 (BTV22_08820)	rpmB	1967865..1968101 (-)	237	WP_011608297.1	50S ribosomal protein L28	-
BTV22_RS08855 (BTV22_08825)	radC	1968322..1968990 (-)	669	WP_011608296.1	RadC family protein	Machinery gene
BTV22_RS08860 (BTV22_08830)	coaBC	1969163..1970389 (+)	1227	WP_075293534.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
BTV22_RS08865 (BTV22_08835)	dut	1970386..1970841 (+)	456	WP_011608294.1	dUTP diphosphatase	-
BTV22_RS08870 (BTV22_08840)	slmA	1970841..1971500 (+)	660	WP_011608293.1	nucleoid occlusion factor SlmA	-
BTV22_RS08875 (BTV22_08845)	-	1971535..1971759 (+)	225	WP_012341336.1	YheU family protein	-
BTV22_RS08880 (BTV22_08850)	crp	1971772..1972416 (+)	645	WP_011608291.1	cAMP-activated global transcriptional regulator CRP	Regulator
BTV22_RS08885 (BTV22_08855)	recF	1972473..1973549 (-)	1077	WP_075293535.1	DNA replication/repair protein RecF	-
BTV22_RS08890 (BTV22_08860)	dnaN	1973553..1974653 (-)	1101	WP_075293536.1	DNA polymerase III subunit beta	-
BTV22_RS08895 (BTV22_08865)	dnaA	1974665..1976023 (-)	1359	WP_011608288.1	chromosomal replication initiator protein DnaA	-
BTV22_RS08900 (BTV22_08870)	rpmH	1976366..1976500 (+)	135	WP_007241546.1	50S ribosomal protein L34	-
BTV22_RS08905 (BTV22_08875)	rnpA	1976515..1976874 (+)	360	WP_011608287.1	ribonuclease P protein component	-
BTV22_RS08910 (BTV22_08880)	yidD	1976838..1977098 (+)	261	WP_011608286.1	membrane protein insertion efficiency factor YidD	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24029.75 Da
• Isoelectric Point: 7.4775

>NTDB_id=176083 BTV22_RS08880 WP_011608291.1 1971772..1972416(+) (crp) [Histophilus somni strain USDA-ARS-USMARC-63373]
MLEQQGQSAPSMDPTLEWFLSHCHIHKYSAKSSLIHAGEKAETLYYLIRGSVAVMVKDEEGKEMILTYLSQGDFFGEAGL
FDETQPRSAWVKAKSSCEIAEISYKKFRQLIQVNPEILMYLAGQLAHRLQNTSKQVSNLAFLDVTGRIAQTLLNLAKMPD
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide

• Length: 645 bp

>NTDB_id=176083 BTV22_RS08880 WP_011608291.1 1971772..1972416(+) (crp) [Histophilus somni strain USDA-ARS-USMARC-63373]
ATGTTAGAACAACAAGGACAATCAGCACCATCGATGGATCCGACGTTAGAGTGGTTCCTATCTCATTGTCACATTCATAA
ATACTCAGCAAAAAGCTCCCTCATTCATGCTGGAGAAAAGGCGGAAACCCTTTATTATTTAATTAGAGGGTCTGTTGCCG
TGATGGTAAAAGATGAGGAAGGTAAAGAAATGATTTTGACTTATTTAAGTCAAGGTGATTTTTTTGGCGAAGCTGGTTTA
TTTGATGAAACACAGCCTCGTTCGGCTTGGGTTAAAGCTAAAAGCTCATGTGAAATTGCAGAAATTTCTTATAAAAAATT
TCGCCAATTAATTCAAGTTAATCCAGAAATTTTAATGTATTTAGCCGGTCAATTAGCTCATCGTTTACAAAATACTTCAA
AGCAGGTAAGCAATTTGGCATTTTTAGATGTGACAGGTCGTATCGCTCAAACCTTGTTAAATTTAGCTAAGATGCCTGAT
GCAATGACTCATCCGGACGGTATGCAAATTAAAATTACTCGTCAGGAAATAGGACAAATGGTAGGTTGCTCACGAGAAAC
TGTTGGGCGTATTTTGAAAATGTTAGAAGATCAGCATTTAATTTCAGCACATGGCAAAACTATTGTTGTGTATGGTACAA
GATAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (146-210)

• Cyclic nucleotide-binding domain (cNMP_binding) (27-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	81.463	95.794	0.78
crp	Haemophilus influenzae Rd KW20	78.846	97.196	0.766
crp	Acinetobacter baumannii D1279779	44.221	92.991	0.411