Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BS635_RS05755 Genome accession   NZ_CP018323
Coordinates   1081247..1081879 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain KSC9     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1076247..1086879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BS635_RS05725 (BS635_05750) yheS 1076416..1078329 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  BS635_RS05730 (BS635_05755) yheT 1078329..1079351 (+) 1023 WP_000057379.1 hydrolase -
  BS635_RS05735 (BS635_05760) yheU 1079345..1079563 (+) 219 WP_000907085.1 YheU family protein -
  BS635_RS05740 (BS635_05765) prkB 1079617..1080486 (+) 870 WP_001274680.1 phosphoribulokinase -
  BS635_RS05745 (BS635_05770) yhfA 1080541..1080945 (-) 405 WP_001148908.1 OsmC family protein -
  BS635_RS05755 (BS635_05780) crp 1081247..1081879 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BS635_RS05760 (BS635_05785) yhfK 1081930..1084020 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  BS635_RS05765 (BS635_05790) argD 1084087..1085307 (-) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BS635_RS05770 (BS635_05795) pabA 1085393..1085956 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  BS635_RS05775 (BS635_05800) fic 1085988..1086590 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  BS635_RS05780 (BS635_05805) yhfG 1086580..1086747 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=174923 BS635_RS05755 WP_000242755.1 1081247..1081879(+) (crp) [Escherichia coli strain KSC9]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=174923 BS635_RS05755 WP_000242755.1 1081247..1081879(+) (crp) [Escherichia coli strain KSC9]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment