Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   A2G56_RS09860 Genome accession   NZ_CP014835
Coordinates   2156980..2157717 (+) Length   245 a.a.
NCBI ID   WP_062712190.1    Uniprot ID   -
Organism   Streptococcus halotolerans strain HTS9     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2151980..2162717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2G56_RS09840 - 2152297..2152989 (-) 693 WP_062712178.1 response regulator transcription factor -
  A2G56_RS09845 - 2153151..2154296 (-) 1146 WP_062712180.1 SSURE domain-containing protein -
  A2G56_RS09850 - 2155047..2156033 (-) 987 WP_062712183.1 bile acid:sodium symporter family protein -
  A2G56_RS09855 - 2156639..2156983 (+) 345 WP_062712187.1 LytTR family DNA-binding domain-containing protein -
  A2G56_RS09860 comE/blpR 2156980..2157717 (+) 738 WP_062712190.1 response regulator transcription factor Regulator
  A2G56_RS09865 - 2157729..2159060 (+) 1332 WP_237334414.1 sensor histidine kinase -
  A2G56_RS10375 - 2159096..2159248 (-) 153 WP_082785140.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  A2G56_RS09870 - 2159439..2160020 (-) 582 WP_157761216.1 HlyD family efflux transporter periplasmic adaptor subunit -
  A2G56_RS10840 - 2160100..2160480 (-) 381 WP_062712196.1 hypothetical protein -
  A2G56_RS09880 comB 2160485..2160760 (-) 276 WP_062712198.1 hypothetical protein Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28887.32 Da        Isoelectric Point: 7.0263

>NTDB_id=174507 A2G56_RS09860 WP_062712190.1 2156980..2157717(+) (comE/blpR) [Streptococcus halotolerans strain HTS9]
MNIFVLEDDFAQQTRMETLIKEIVAKHKLDVESVEVYGKPDHLLAASKEKGAHQLFFLDIEIKNDDMKGLKVAKEITYKD
PYANIVFVTTHSEFMPLSFRYQIKALDYIDKELETVNFEKRIEDNILYAQTRDNKRVIEDSFYFQSKYNQIQYPFKDLLY
IETSPRPHRVILHTAVDRMEFTASLSDIVKQDRRLLQCHRSFVINPMNVIKVDRHERIAYLKDGSTCLVARHKMDLLLKT
IADLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=174507 A2G56_RS09860 WP_062712190.1 2156980..2157717(+) (comE/blpR) [Streptococcus halotolerans strain HTS9]
ATGAATATTTTTGTATTAGAGGATGATTTTGCGCAACAGACACGGATGGAAACACTTATTAAAGAGATTGTTGCTAAACA
TAAGTTAGACGTTGAAAGTGTTGAAGTGTATGGTAAGCCCGACCATTTATTAGCAGCATCAAAAGAAAAGGGAGCCCATC
AATTATTCTTTTTAGATATTGAAATTAAAAATGATGATATGAAAGGGTTAAAAGTAGCTAAGGAAATCACGTATAAAGAT
CCTTACGCAAACATTGTTTTTGTGACCACACACTCAGAATTTATGCCCCTGTCATTTAGGTATCAAATCAAAGCCTTAGA
CTATATTGACAAAGAATTGGAAACGGTCAATTTTGAAAAGCGTATTGAAGATAATATCCTATACGCACAGACAAGAGATA
ATAAAAGGGTGATAGAAGATTCCTTTTATTTTCAATCAAAATATAACCAAATTCAGTATCCTTTTAAGGATTTGCTTTAT
ATAGAAACATCACCACGTCCACATCGCGTCATCCTTCATACGGCTGTTGATCGCATGGAATTTACGGCTAGTTTATCAGA
TATTGTTAAGCAGGATAGGCGATTGCTACAATGTCATAGATCTTTTGTTATTAATCCTATGAATGTCATCAAGGTGGATA
GGCATGAGCGGATTGCTTATTTAAAGGACGGTTCAACGTGTTTAGTTGCACGTCATAAAATGGATCTTTTACTGAAGACC
ATAGCTGATTTGCATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

49.18

99.592

0.49
  comE/comE1 Streptococcus equinus JB1

42.017

97.143

0.408

Multiple sequence alignment