Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BFL22_RS23335 Genome accession   NZ_CP018239
Coordinates   4193863..4194495 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 272     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4188863..4199495
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFL22_RS23305 (BFL22_23030) yheS 4189032..4190945 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  BFL22_RS23310 (BFL22_23035) yheT 4190945..4191967 (+) 1023 WP_000057377.1 hydrolase -
  BFL22_RS23315 (BFL22_23040) yheU 4191961..4192179 (+) 219 WP_000907085.1 YheU family protein -
  BFL22_RS23320 (BFL22_23045) prkB 4192233..4193102 (+) 870 WP_001274677.1 phosphoribulokinase -
  BFL22_RS23325 (BFL22_23050) yhfA 4193157..4193561 (-) 405 WP_001148908.1 OsmC family protein -
  BFL22_RS23335 (BFL22_23060) crp 4193863..4194495 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BFL22_RS23340 (BFL22_23065) yhfK 4194546..4196636 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  BFL22_RS23345 (BFL22_23070) argD 4196703..4197923 (-) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BFL22_RS23350 (BFL22_23075) pabA 4198009..4198572 (-) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  BFL22_RS23355 (BFL22_23080) fic 4198604..4199206 (-) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  BFL22_RS23360 (BFL22_23085) yhfG 4199196..4199363 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=174249 BFL22_RS23335 WP_000242755.1 4193863..4194495(+) (crp) [Escherichia coli strain 272]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=174249 BFL22_RS23335 WP_000242755.1 4193863..4194495(+) (crp) [Escherichia coli strain 272]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment