Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   BSR19_RS02365 Genome accession   NZ_CP018187
Coordinates   456289..457041 (+) Length   250 a.a.
NCBI ID   WP_060973375.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC2     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 451289..462041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS02350 (BSR19_02350) - 452172..452864 (+) 693 WP_038675425.1 DUF6287 domain-containing protein -
  BSR19_RS02355 (BSR19_02355) - 452929..453228 (+) 300 WP_060973374.1 hypothetical protein -
  BSR19_RS02360 (BSR19_02360) - 453505..456087 (+) 2583 WP_060973380.1 SH3 domain-containing protein -
  BSR19_RS02365 (BSR19_02365) comE/blpR 456289..457041 (+) 753 WP_060973375.1 LytR/AlgR family response regulator transcription factor Regulator
  BSR19_RS02370 (BSR19_02370) - 457176..457841 (+) 666 WP_156246406.1 DUF6287 domain-containing protein -
  BSR19_RS02375 (BSR19_02375) comE/blpR 458089..458823 (+) 735 WP_060973247.1 response regulator transcription factor Regulator
  BSR19_RS11560 - 458820..459104 (+) 285 WP_231605975.1 hypothetical protein -
  BSR19_RS11565 comD/blpH 459284..460114 (+) 831 WP_231605976.1 sensor histidine kinase Regulator
  BSR19_RS02385 (BSR19_02385) - 460212..460778 (+) 567 WP_156246408.1 transcriptional regulator -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28709.06 Da        Isoelectric Point: 5.1986

>NTDB_id=173601 BSR19_RS02365 WP_060973375.1 456289..457041(+) (comE/blpR) [Streptococcus salivarius strain ICDC2]
MLDIFVLEEDYFQQARLEDAIHKSKQIYILRIGKVNLYDKPNQLLERITERGSHLLFFLDIGSDSDIEGGILVAQQIRER
DPYASIVFITAHPELLPSTFQYRLAALDFIDKNLPDNEYEDRIISDIGLALSKNGLSQIECAFTVDTKNATIQVPFHKIL
YFETSPTVHKVILHTTEEQIEFYGQLSEIVKQDCRLYKCHKSFVVNPENIVRLDKELGIIYFENGESCLVSKAKQKEIVA
KMLVPKTIAV

Nucleotide


Download         Length: 753 bp        

>NTDB_id=173601 BSR19_RS02365 WP_060973375.1 456289..457041(+) (comE/blpR) [Streptococcus salivarius strain ICDC2]
ATGTTAGATATTTTTGTTTTAGAAGAAGATTATTTTCAACAAGCTCGTCTTGAGGATGCCATCCACAAGTCTAAACAAAT
ATATATTTTAAGAATTGGGAAGGTCAATTTATACGATAAACCCAATCAATTATTAGAGCGTATTACGGAAAGGGGCTCGC
ATTTACTCTTTTTTCTAGATATTGGATCTGATAGTGATATCGAAGGGGGAATATTGGTTGCTCAACAGATTCGTGAGCGA
GATCCTTATGCTAGTATTGTTTTCATCACAGCACATCCCGAACTCCTACCTTCAACCTTTCAGTATCGCTTAGCTGCACT
TGATTTTATTGATAAGAATTTGCCTGATAATGAATATGAAGATAGGATTATTTCTGATATTGGATTAGCACTTTCTAAAA
ATGGTCTTAGCCAAATAGAGTGTGCTTTTACGGTAGATACAAAGAATGCAACTATACAAGTTCCTTTTCATAAGATTCTT
TATTTTGAAACATCTCCAACAGTTCATAAGGTGATTCTTCATACAACGGAAGAGCAGATCGAGTTCTATGGTCAATTGTC
AGAAATTGTGAAACAAGATTGCAGACTATATAAATGCCATAAATCATTTGTTGTAAATCCCGAAAACATTGTGAGGTTGG
ACAAAGAGTTAGGTATTATTTATTTTGAAAACGGAGAGTCATGCTTGGTTTCAAAAGCTAAACAAAAAGAGATTGTAGCT
AAGATGCTTGTTCCAAAAACCATAGCAGTTTGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

46.091

97.2

0.448
  comE/comE1 Streptococcus equinus JB1

42.149

96.8

0.408