Detailed information NTG0173465

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: BSR14_RS00300
• Genome accession: NZ_CP018186
• Coordinates: 50445..52976 (+)
• Length: 843 a.a.
• NCBI ID: WP_414355357.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ICDC1
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 45445..57976

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR14_RS00280 (BSR14_00280)	purB	45619..46917 (+)	1299	WP_049527584.1	adenylosuccinate lyase	-
BSR14_RS00285 (BSR14_00285)	argS	47792..49483 (-)	1692	WP_045772358.1	arginine--tRNA ligase	-
BSR14_RS00290 (BSR14_00290)	argR	49638..50066 (+)	429	WP_170314548.1	arginine repressor	-
BSR14_RS00295 (BSR14_00295)	-	50066..50425 (+)	360	WP_045772359.1	YlbF family regulator	-
BSR14_RS00300 (BSR14_00300)	hexA	50445..52976 (+)	2532	WP_414355357.1	DNA mismatch repair protein MutS	Machinery gene
BSR14_RS00305 (BSR14_00305)	-	53010..53465 (-)	456	WP_049527571.1	DUF3021 domain-containing protein	-
BSR14_RS00310 (BSR14_00310)	-	53462..53899 (-)	438	WP_045772361.1	LytTR family DNA-binding domain-containing protein	-
BSR14_RS00315 (BSR14_00315)	-	54078..54383 (+)	306	WP_002886319.1	hypothetical protein	-
BSR14_RS00320 (BSR14_00320)	hexB	54433..56370 (+)	1938	WP_021143432.1	DNA mismatch repair endonuclease MutL	Machinery gene
BSR14_RS00325 (BSR14_00325)	-	56501..56722 (+)	222	WP_002886321.1	hypothetical protein	-
BSR14_RS00330 (BSR14_00330)	ruvA	56879..57469 (+)	591	WP_014633718.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94609.58 Da
• Isoelectric Point: 4.6329

>NTDB_id=173465 BSR14_RS00300 WP_414355357.1 50445..52976(+) (hexA) [Streptococcus salivarius strain ICDC1]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIVERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDAIYTRIGASD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQEKPATETHI
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=173465 BSR14_RS00300 WP_414355357.1 50445..52976(+) (hexA) [Streptococcus salivarius strain ICDC1]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTCCGTATGGGTGATTTTTACGAATTATT
TTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCCGATAATCCCATTC
CTATGGCTGGTGTTCCTTATCATTCAGCTCAATCCTATATTGATGTCTTGGTTGAGATGGGCTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGGCTGGAAGTCGTTTTGGTCTGGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCAGTTTGTAGTGAAATTCAGAACCTTAAG
GCACGTGAAGTAGTAGTTGGTTATGATTTACCTGAAGCTGATGAACAAGTTTTGGTGAAGCAACTCAACCTTCTACTCTC
TAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAGACTTAGAAAGCAGTGTAGCGGGTAAAC
TTCTCCAATATGTGCACCGTACTCAGATGCGTGAGCTCAGCCATTTACAAAAGGCTCAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTGCTGGAAAATGCTAGAACAGGTAAGAAACACGGTTCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGTACTTGGATTGACCGTCCTTTAGTGAATCAGG
CTGCAATCGTGGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTCGAGCGTAGTGACCTGACAGAGAGTCTT
AAAGGGGTTTACGACATTGAGCGCTTGGCTAGTCGTGTTTCCTTCGGAAAGGCTAACCCTAAAGATTTGATTCAGCTAGG
TCATACCCTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTAATGATGAGGCCTTGTCACGTCTTTTACAAG
AATTGGATGCTCTGCCAGAATTAGAGAGTCTGATTCGGTCGGCTATTGATCCCGATGCTCCTGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGCGAGGGGACATCGTGGATCGCAGA
TATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATAGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAATCTTAGCTTGGTTCCTGACCACTTCTTCCGCAAGGCAACTCTGAAAAACTCAGAGCGCTTCGGA
ACTGCTGAGTTGGCTAAGATTGAAGGTGAGATGCTCGAGGCACGTGAAAAGTCATCAACGCTAGAGTATGATATTTTCAT
GCGTGTCCGTGAGCAGGTGGAACGCTATATTGATCGTTTGCAATCTTTGGCTAAGGCTATTGCGACAGTCGATGTACTTC
AGAGTTTGGCAGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAGCATCGTATCGTTATTGATCAA
GGCCGTCATGCGGTGGTTGAGAAGGTTATGGGTGTTCAGGAATACATTCCAAACACGATTACCTTTGACAGTCAGACCAA
TGTTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCTACTTATATGCGTCAGTTGGCCTTGTCAGTCGTTATGGCTC
AGATGGGGTCTTACGTACCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCCATCTATACGCGTATTGGTGCTTCAGAT
GACCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCCATTAAGCGCGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTGGGGCGTGGGACAGCCACCTATGATGGTATGGCTTTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTGGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCCGA
TAAATCTTACGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AATTAGAGGGCGAGACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAGCCTGCCACTGAAACGCATATC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCGGTTCTTCAAGAGTTACGTGATTTGGATATTTACAATAT
GACACCGATGCAGGTCATGATGGCTGTAGCAGATTTGAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (590-776)

• MutS domain III (MutS_III) (247-537)

• MutS domain I (MutS_I) (1-109)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain II (MutS_II) (117-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.815	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	36.079	100	0.369