Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   A0O21_RS07160 Genome accession   NZ_CP014699
Coordinates   1558163..1559461 (-) Length   432 a.a.
NCBI ID   WP_067063544.1    Uniprot ID   A0A172Q8L6
Organism   Streptococcus pantholopis strain TA 26     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1553163..1564461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS07150 (A0O21_07150) hpf 1556876..1557427 (-) 552 WP_067063536.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  A0O21_RS07155 (A0O21_07155) comFC/cflB 1557501..1558163 (-) 663 WP_067063540.1 ComF family protein Machinery gene
  A0O21_RS07160 (A0O21_07160) comFA/cflA 1558163..1559461 (-) 1299 WP_067063544.1 DEAD/DEAH box helicase Machinery gene
  A0O21_RS07165 (A0O21_07165) - 1559519..1560163 (+) 645 WP_067063548.1 YigZ family protein -
  A0O21_RS07170 (A0O21_07170) cysK 1560382..1561311 (+) 930 WP_067063551.1 cysteine synthase A -
  A0O21_RS07175 (A0O21_07175) - 1561463..1561825 (-) 363 WP_067063554.1 S1 RNA-binding domain-containing protein -
  A0O21_RS07180 (A0O21_07180) - 1561825..1563225 (-) 1401 WP_067063558.1 Cof-type HAD-IIB family hydrolase -
  A0O21_RS07185 (A0O21_07185) - 1563267..1563908 (-) 642 WP_067063562.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 48875.03 Da        Isoelectric Point: 10.0296

>NTDB_id=173362 A0O21_RS07160 WP_067063544.1 1558163..1559461(-) (comFA/cflA) [Streptococcus pantholopis strain TA 26]
MDDLDNFYGRQFTEDQLPAEIQKQAQTYPAAVKKGNHWFCVRCSARIPFEAILPDGSYYCRDCLVFGRISTDMQLYFFPQ
KSFPPVHSLIWSGRLTSYQKQVSDALLASLKKRESVLIHAVTGAGKTEMIYKAVAYVIDQGGAVCVASPRIDVCIELYKR
LTSAFSCLVTLLHGSSEPYRRSPLLIATTHQLLKFYQAFDLLIIDEVDAFPFIGNSMLYYAVNRCIREKGLKIFLTATPT
AALERKVREGEIKKLYLARRFHGSPLVVPKTQWLGNLLKKMSRGRLPRKLIATIKRQRQSGFPLLLFFPIIEQGEELTAI
LRQYFPNEAIAHVSSQSGDRLKCVEDFRSGKIHILVSTTILERGVTFPKIDVYVLLAHHHLYTKSSLVQLAGRVGRSKVR
SSGELIFFHSGVTKAIQKAISEIKEMNQKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=173362 A0O21_RS07160 WP_067063544.1 1558163..1559461(-) (comFA/cflA) [Streptococcus pantholopis strain TA 26]
ATGGATGATTTAGATAATTTCTATGGCCGTCAATTTACCGAGGACCAGCTGCCTGCAGAAATTCAAAAGCAGGCTCAGAC
TTATCCTGCAGCCGTTAAAAAAGGAAATCATTGGTTTTGTGTGCGCTGTTCTGCTCGAATTCCTTTTGAAGCGATTTTGC
CAGACGGTTCATACTACTGCAGGGACTGTCTGGTTTTTGGTAGAATTTCGACCGACATGCAGCTATATTTTTTCCCCCAG
AAAAGCTTCCCTCCTGTTCATTCTCTGATTTGGTCGGGCAGGCTGACTTCCTATCAAAAGCAAGTATCTGATGCCTTACT
AGCCAGTCTGAAAAAAAGAGAAAGTGTTTTAATCCACGCGGTGACAGGAGCAGGTAAAACGGAAATGATATATAAAGCAG
TCGCCTATGTAATTGATCAAGGAGGAGCTGTCTGTGTTGCCAGTCCTAGGATCGATGTCTGCATTGAATTATATAAGCGC
CTCACTTCTGCATTTTCATGTTTAGTGACACTCTTACATGGTAGTTCTGAGCCTTACAGACGTTCTCCCTTGCTCATTGC
GACAACCCACCAGCTGCTAAAATTTTATCAGGCATTTGACTTATTAATTATTGATGAAGTCGATGCTTTTCCTTTTATAG
GGAATTCTATGCTTTACTATGCAGTGAACAGATGCATACGCGAAAAGGGATTGAAAATTTTTCTAACGGCAACTCCAACC
GCAGCACTGGAAAGAAAGGTAAGAGAAGGAGAGATAAAAAAGCTGTATCTTGCTCGTCGTTTTCATGGCAGTCCGCTGGT
TGTTCCCAAAACACAGTGGCTGGGGAATCTGTTGAAAAAGATGTCTAGAGGCAGACTCCCCCGAAAATTAATCGCAACAA
TAAAGCGACAAAGACAAAGCGGTTTTCCTTTGCTACTGTTTTTTCCAATTATAGAACAGGGAGAAGAATTAACAGCTATT
TTGCGGCAGTACTTTCCTAATGAAGCGATAGCTCATGTTTCCAGCCAATCAGGGGATCGCTTGAAATGTGTGGAGGATTT
TCGCAGCGGAAAGATTCACATTCTTGTCTCAACAACTATTCTGGAACGCGGTGTTACGTTCCCAAAGATTGACGTTTATG
TATTGCTGGCTCATCACCATCTATACACTAAAAGCAGTTTAGTTCAGCTAGCCGGACGTGTTGGCCGTTCGAAAGTCAGA
TCTTCCGGAGAACTAATCTTTTTTCATAGTGGTGTAACTAAAGCTATCCAAAAAGCGATTTCAGAGATTAAGGAAATGAA
TCAAAAAGGAGGATTCTGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(95-239)

Helicase conserved C-terminal domain (Helicase_C)

(289-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172Q8L6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.504

98.843

0.549
  comFA/cflA Streptococcus pneumoniae D39

55.504

98.843

0.549
  comFA/cflA Streptococcus pneumoniae R6

55.504

98.843

0.549
  comFA/cflA Streptococcus pneumoniae TIGR4

55.504

98.843

0.549
  comFA/cflA Streptococcus mitis NCTC 12261

55.504

98.843

0.549
  comFA/cflA Streptococcus mitis SK321

54.801

98.843

0.542
  comFA Lactococcus lactis subsp. cremoris KW2

45.75

92.593

0.424
  comFA Latilactobacillus sakei subsp. sakei 23K

38.161

100

0.384

Multiple sequence alignment